The article presents treatment results of the dry eye syndrome after excimer laser refractive surgery (LASIK). This procedure often leads to dry eye symptoms and signs, so there should be a mandatory prescription of lubricative eye drops for up to 3-6 months. For treatment, non-preserved Gilan Comfort containing hyaluronic acid (Russian Federation trade mark) was used. The study included 30 patients after LASIK who received Gilan Comfort 4 times a day for 3 months. Treatment was well tolerated; there were no adverse effects in any of the patients. The treatment results observed in all 30 people consisted in distinct decrease of dry eye symptoms after 3 months of Gilan Comfort instillations after LASIK surgery. (For citation: Astakhov SYu, Riks IA. Experience in Gilan Comfort eye drops use of in patients after excimer laser surgery. Ophthalmology Journal. 2017;10(4):57-60. doi: 10.17816/OV10457-60).