Post-operative adhesions after digestive surgery: Their incidence and prevention: Review of the literature

Ouaïssi, Mehdi; Gaujoux, Sébastien; Veyrie, Nicolas; Denève, E.; Brigand, Cécile; Castel, Benjamin; Duron, Jean‐Jacques; Rault, A.; Slim, K.; Nocca, David

doi:10.1016/j.jviscsurg.2011.11.006

Cited by 164 publications

(126 citation statements)

References 81 publications

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“…How- ever, several studies have reported negative results of Seprafilm [15][16][17][18] . Studies have described how Seprafilm was not useful in preventing BO, although it was effective in preventing adhesion 15,18) . In our study, Seprafilm was effective in preventing BO after colorectal cancer surgery.…”

Section: Discussionmentioning

confidence: 99%

“…Various products and postoperative management procedures have been used to prevent postoperative peritoneal adhesions [1][2][3][4][5][6][7][8] . The usefulness of the absorptive anti-adhesion barrier film Seprafilm [9][10][11][12][13][14] has been shown by many randomized control studies and meta-analysis, although studies with negative results do exist [15][16][17][18] . Interestingly, the reports on peritoneal adhesion or BO associated with laparoscopic surgery, the use of which has rapidly spread in recent years, are few compared with reports on open surgery 11,[19][20][21][22][23] .…”

Section: Introductionmentioning

confidence: 99%

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Absorptive anti-adhesion barrier for the prevention of bowel obstruction after laparoscopic colorectal cancer surgery

Fujii

Tsukamoto

Shimada

et al. 2018

J Anus Rectum Colon

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Abstract:Objectives: The protective efficacy of an absorptive adhesion prevention product (Seprafilm ) against bowel obstruction (BO) during open surgery was demonstrated in a large-scale randomized controlled clinical trial in Europe and America. However, the efficacy of Seprafilm against BO in laparoscopic surgery remains uncertain. The objective of this study was to clarify the protective efficacy of Seprafilm against BO after laparoscopic surgery for colorectal cancer. Methods: From 2009 to 2016, 1328 laparoscopic colorectal resections were performed for colorectal cancer. From 2009, Seprafilm was used for preventing BO in laparoscopic colorectal surgery. The incidence of BO and short-term results were compared between the Seprafilm and non-Seprafilm groups after propensity score matching. Results: Propensity scoring generated 270 matched patients per group for the comparisons between the Seprafilm and non-Seprafilm groups. The two groups showed no significant differences regarding patients' backgrounds. Among all patients, 73.1% (19/26) of BO occurred within 30 days after the surgery. Significantly lower incidences of all grade (2.6% vs. 7.0%; p = 0.016) and grade 2 + 3a (1.5% vs. 5.2%; p = 0.017) BO were observed in the Seprafilm group than in the non-Seprafilm group; no significant difference regarding grade 3b BO (1.1% vs. 1.9%; p = 0.476) was found. A significant difference in BO within 30 days was also noted between the two groups (1.9% vs. 5.2%, p = 0.036). There were no significant differences between the groups regarding anastomotic leakage and deep surgical site infection. Conclusions: Seprafilm was useful for preventing BO, requiring decompression therapy of the bowel, after laparoscopic colorectal surgery without increasing adverse events.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Absorptive anti-adhesion barrier for the prevention of bowel obstruction after laparoscopic colorectal cancer surgery

Fujii

Tsukamoto

Shimada

et al. 2018

J Anus Rectum Colon

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“…Furthermore, those advocating urgent surgery for AIO also note that approximately 60% of all cases could be improved without surgery [5]. Conservative management of AIOs is also widely applied in adult age groups [11]. The incidence of intestinal injury and recurrent adhesions following operations performed for adhesive intestinal obstruction have been reported from 11-52% (5,10,12,13).…”

Section: Discussionmentioning

confidence: 99%

Evaluation of a Series of Patients Operated For Adhesive Intestinal Obstructions

Ertürk¹,

Sönmez²,

Kale³

2017

Int J Surg Med

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Background:The risk of bowel obstruction after laparotomy in infants and children, especially in developing countries, has not been well researched. Objectives: The aim of this study was to perform a detailed analysis of adhesions and the risk factors for adhesion-associated intestinal obstruction after laparotomy in children. Methods: This retrospective study involved patients who were operated between January 1990 and January 2001 on for postoperative adhesive intestinal obstruction (AIO). Results:A total of 45 patients (mean 7.75 years) were operated on after 1341 laparotomies. The incidence of AIO was 3.35%. The patients were operated on at 6th postoperative day at the earliest and 10 years at the latest. The mortality and morbidity rates were found to be 2.2% and 22.2%, respectively. AIO was most commonly observed after operations involving the pelvic area (77.7%). Appendectomy, trauma, invagination, and megacolon surgeries were the most common postoperative causes of AIO. Conclusion:This study showed that adhesions in children occurred more commonly after lower abdominal surgery. The risks were closely related to the site and type of the first surgery. Although the risk of having adhesions was very high in the first years, it also persists in the following years.

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“…While the conservative treatment of nasogastric decompression can be uncomfortable for the patient, the postoperative complications from adhesiolysis can be catastrophic. Paralytic ileus, wound infection, chronic abdominal pain, and enterocutaneous fistula from iatrogenic enterotomy are all within the spectrum of complications [9]- [11]. Therefore it is critical to identify a way to minimize the peritoneal adhesion burden after initial laparotomy.…”

Section: Discussionmentioning

confidence: 99%

Risk Factors for the Development of Adhesive Small Bowel Obstruction after Abdominal and Pelvic Operations

Sastry¹,

Grigor'eva²,

Leitman³

2015

OJGas

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Post-operative adhesions after digestive surgery: Their incidence and prevention: Review of the literature

Cited by 164 publications

References 81 publications

Absorptive anti-adhesion barrier for the prevention of bowel obstruction after laparoscopic colorectal cancer surgery

Absorptive anti-adhesion barrier for the prevention of bowel obstruction after laparoscopic colorectal cancer surgery

Evaluation of a Series of Patients Operated For Adhesive Intestinal Obstructions

Risk Factors for the Development of Adhesive Small Bowel Obstruction after Abdominal and Pelvic Operations

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