Post‐prostate biopsy acute bacterial prostatitis and screening cultures using selective media: An overview

Abstract

The development of several culture media and the availability to isolate and treat pathogens prior to a surgical procedure give us the ability to minimize treatmentrelated complications, and ultimately results in better outcomes for patients and avoidance of unwanted post-procedure inpatient admissions. In the last decade, an increasing incidence of multidrug-resistant Escherichia coli, especially extended-spectrum beta-lactamase-producing E. coli and fluoroquinolone-resistant pathogens, has been reported. These resistant species frequently colonize the rectal flora and gain access to the systemic circulation via the rectal plexus following a prostate biopsy. The bacteria can eventually lead to life-threatening complications, which is especially important in high-risk patients with multiple co-morbidities. Previously published studies have focused on the isolation of these pathogens with selective media before an invasive procedure and the potential benefits of incorporating the use of selective media as a mandatory pre-operative step. This preventive measure will allow us to offer a tailored prophylactic treatment that benefits patients and reduces the economic burden for the hospital.

Prostate tissue ablation and drug delivery by an image-guided injectable ionic liquid in ex vivo and in vivo models

“…Invasive clinical prostate procedures, particularly those using a transrectal approach, have a risk of infectious complications because of rectal flora ( 36 ). Resistant strains of Escherichia coli are responsible for approximately 80% of bacterial prostatitis cases ( 37 ). To assess whether PADA delivery to the prostate tissue can protect against potential procedure-related infections, we conducted susceptibility studies using some of the most antibiotic-resistant pathogens obtained from infected patients at the Mayo Clinic.…”