Post‐prostatectomy urinary incontinence

Gimson, Eliza; Majidian, Daniel; Mukhammadaminov, Anvarjon; Taylor, Claire; Malde, Sachin; Sahai, Amit

doi:10.1002/tre.686

Cited by 1 publication

(1 citation statement)

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“…Surgical procedures used to treat SUI are associated with several complications such as urinary incontinence, 14 bladder defect, frequent urinary tract infection, 15 pain, and sexual problems 16 . Given the multifaceted challenges associated with surgical procedures and the absence of research on the effects of duloxetine in the context of SUI treatment in Iranian women, this study endeavors to evaluate the efficacy of duloxetine in the management of SUI in women.…”

Section: Introductionmentioning

confidence: 99%

The effect of duloxetine on stress urinary incontinence

Lorzadeh,

Jahanshahi

2024

Health Science Reports

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Background and AimsThis study aims to evaluate the effect of duloxetine on stress urinary incontinence (SUI) episode frequency (IEF) per week IEF.MethodsIn this clinical trial, 100 women aged 20−80 years with urinary incontinence were assessed based on the standard questionnaire of urinary tract disorders. All the patients received a placebo for 2 weeks. Patients were then randomly divided into two groups of 50 patients each, receiving duloxetine (40 mg twice a day for 12 weeks) and placebo. The two groups were compared in terms of IEF and the mean score of quality of life and side effects.ResultsThe two groups of duloxetine and placebo recipients were matched at the beginning of the study in terms of age, BMI, IEF, parity, and type of delivery. IEF significantly decreased in the duloxetine recipient group compared to the placebo group. The mean score of quality of life in the duloxetine recipient group increased significantly. The rate of study abandonment in the duloxetine recipient group was significantly higher than in the placebo group. Vertigo was the most common complication that caused patients to discontinue the use of the drug.ConclusionDuloxetine is therapeutically effective for SUI in women. Patients should be provided information regarding potential side effects and their management.

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Section: Introductionmentioning

confidence: 99%