Post‐steroid panniculitis in an adult

Kim, Tae Kwon; Lee, Jin Woo; Roh, Hyo Jin; Choi, Soo Young; Jeon, Young Seung; Suh, Kee Suck

doi:10.1111/j.1346-8138.2008.00570.x

Cited by 11 publications

(3 citation statements)

References 10 publications

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“…In the adult population, only one case has been reported. [5] Patients who have developed this variant of panniculitis have received high doses of systemic corticosteroids for a variety of conditions, including rheumatic fever, leukemia, nephrotic syndrome, secretory diarrhea, brain stem glioma, and cerebral edema. [6] Clinically, cutaneous lesions of post-steroid panniculitis consist of erythematous subcutaneous nodules and plaques that appear 1–10 days after stopping high doses of systemic corticosteroids.…”

Section: Discussionmentioning

confidence: 99%

Post-steroid panniculitis: A rare case report

Sacchidanand

Shilpa

Somaiah

et al. 2013

Indian Dermatol Online J

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Post-steroid panniculitis (PSP) is a rare clinical entity which presents after rapid withdrawal of high doses of systemic corticosteroids. As few as 20 cases have been reported in literature till now. Here, we report a case of post-steroid panniculitis occurring in a 9-year-old boy after rapid tapering and discontinuation of corticosteroids administered for the treatment of nephrotic syndrome. He presented with multiple erythematous painful indurated nodules over the face, arms, forearms, thighs, and legs. Histopathologic examination of the nodule revealed lobular panniculitis with lymphocytes, neutrophils, and multiple multinucleated giant cells. It also showed multiple needle-shaped clefts. Based on history, clinical features, and histopathologic findings, a diagnosis of post-steroid panniculitis was made and the patient was restarted on systemic corticosteroids. The lesions resolved in 4 weeks. We report this case to highlight the importance of gradual tapering of corticosteroids.

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Section: Discussionmentioning

confidence: 99%

Post-steroid panniculitis: A rare case report

Sacchidanand

Shilpa

Somaiah

et al. 2013

Indian Dermatol Online J

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“…The nodules tend to appear in those areas prone to accumulation of fat during steroid therapy such as the cheeks, jawline, arms and trunk, although it has also been reported on the legs. Usually there are no general symptoms [40,41].…”

Section: Primarily-lobular Panniculitides Primarily-lobular Panniculimentioning

confidence: 99%

“…The lesions generally subside in weeks or months even without any treatment, leaving residual hyperpigmentation. If ulceration occurs in late stage, resuming steroid therapy may be indicated and then a slower and gradual decrease of the dose should be programmed [40,41].…”

Section: Primarily-lobular Panniculitides Primarily-lobular Panniculimentioning

confidence: 99%

Panniculitides of particular interest to the rheumatologist

Morita

Trés

García³

et al. 2019

Adv Rheumatol

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The panniculitides remain as one of the most challenging areas for clinicians, as they comprise a heterogeneous group of inflammatory diseases involving the subcutaneous fat with potentially-shared clinical and histopathological features. Clinically, most panniculitides present as red edematous nodules or plaques. Therefore, in addition to a detailed clinical history, a large scalpel biopsy of a recent-stage lesion with adequate representation of the subcutaneous tissue is essential to specific diagnosis and appropriate clinical management. Herein we review the panniculitides of particular interest to the rheumatologist.

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Panniculitis

Requena

2016

Rook's Textbook of Dermatology, Ninth Edition

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The panniculitides comprise a group of heterogeneous inflammatory diseases that involve the subcutaneous fat. Histopathological study is required for the specific diagnosis of these disorders, because different panniculitides usually show the same clinical appearance – which typically consists of erythematous nodules on the lower extremities. However, the histopathological study of panniculitis is difficult because of the poor correlation between clinical and pathological findings and the changing microscopic appearances as the lesions evolve. Furthermore, large scalpel incisional biopsies are required in order to evaluate panniculitis fully. From the histopathological point of view, all panniculitides are somewhat mixed, because the inflammatory infiltrate involves both the septa and lobules. However, differentiation between a predominantly septal and a predominantly lobular panniculitis is usually straightforward at scanning magnification on the basis of which subcutaneous structures are the more intensely involved by the inflammatory infiltrate.

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Post‐steroid panniculitis in an adult

Cited by 11 publications

References 10 publications

Post-steroid panniculitis: A rare case report

Post-steroid panniculitis: A rare case report

Panniculitides of particular interest to the rheumatologist

Panniculitis

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