Post-stroke medication adherence and persistence rates: a meta-analysis of observational studies

Zhang, Jia; Gong, Yanhong; Zhao, Yuxin; Jiang, Nan; Wang, Jing; Yin, Xiaoxv

doi:10.1007/s00415-019-09660-y

Cited by 44 publications

(38 citation statements)

References 47 publications

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“…Despite the high prevalence of PSF 2 and its obvious effects on treatment adherence 102 , in practice, only half of recent stroke guidelines have clinical recommendations on PSF. Of those that do, two guidelines provide only brief recommendations, and only one provides comprehensive recommendations, but these are based on low levels of evidence 48 .…”

Section: Discussionmentioning

confidence: 99%

Post-stroke fatigue: a scoping review

et al. 2020

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Background: Post-stroke fatigue (PSF) is one of the most common and frustrating outcomes of stroke. It has a high prevalence and it can persist for many years after stroke. PSF itself contributes to a wider range of undesirable outcomes that affect all aspects of daily life. The aim of this review was to identify and summarise the most recent research on PSF, in order to update the evidence base. Methods: We updated an existing review (Hinkle et al. 2017) systematically searching CINAHL, MEDLINE, PsycINFO, and PubMed to cover new research studies between 1st March 2016 and the search date (19th January 2020). We included interventional and observational research, and clinical practice guidelines that were not covered in the original review. After duplicate removal in EndNote, two reviewers screened the search results in Rayyan, and data from eligible full texts were extracted onto an Excel spreadsheet. Finally, we used RobotReviewer and a human reviewer to assess the risk of bias of randomised trials for this scoping review. Results: We identified 45 records for 30 studies (14 observational, 10 interventional studies, and 6 guidelines). Apart from one, the interventional studies were single-centred, had high risk of bias and small sample size (median 50). They investigated exercise, pharmacotherapy, psychotherapy, education, and light therapy. Observational studies mainly reported the factors related to PSF including co-morbidities, depression and anxiety, quality of life, activities of daily living, stroke severity, medication use and polypharmacy, polymorphism, pain, apathy, limb heaviness, neuroticism, mobility, and thyroid-stimulating hormone. Guidelines either did not report on PSF or, when reported, their recommendations were supported by little or low level of evidence. Conclusion: Although we identified a number of recent studies which have added to our current knowledge on PSF, none are robust enough to change current clinical practice.

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Section: Discussionmentioning

confidence: 99%

Post-stroke fatigue: a scoping review

et al. 2020

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“…In a meta‐analysis, it was emphasized that drug adherence and its effective factors should be considered in the treatment of participants with stroke. Disease prevention and more accurate management strategies are needed for participants with stroke and various comorbidities (Zhang et al, 2019).…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the “partnership care model” on quality of life and activity of daily living in stroke patients: A randomized clinical trial

Mohammadi

Hassandoost

Mozhdehipanah

2021

Japan Journal Nursing Sci

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Background: Stroke is a widespread chronic disease which remains a serious problem for public health and is the cause of major disability and death in adults. Despite valuable efforts, these patients still need new care programs for recovery and rehabilitation. Aim: The aim of this study is to determine the effect of the partnership care model (PCM) on quality of life (QOL) and activities of daily living (ADL) in stroke participants. Method: The study is a randomized clinical trial carried out in an educational and therapeutic center in 2019. Sixty-seven participants (allocated randomly in intervention and control groups) with cerebrovascular accident who had hospitalization histories were selected. Data collection instruments were the Stroke-Specific QOL scale and Lawton questionnaires. The care plan was developed and implemented for the intervention group after evaluating and recording basic information including demographic variables, care needs, and problems identified in the first PCM-based stage. Ethics approval was obtained from the University / Regional Research Ethics Committee (IR.NIMAD.REC.1397.236). Results: The results show that the mean scores of the QOL significantly increased after the intervention in the intervention group (before = 130.80; 3 months = 172.19; 6 months = 205.29) compared to the control group (before = 150; 3 months = 144.86; 6 months = 160.66). Also, the mean scores of the ADL significantly increased after the intervention in the intervention group (before = 1.96; 3 months = 3.64; 6 months = 4.87) compared to the control group (p <.05). The effect size is equal to 0.501 and 0.245 for QOL and ADL, respectively. Conclusion: The findings show that the care program based on a PCM recovered the QOL and ADL of stroke participants more than other interventions.

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“…An algorithm was created to determine whether or not patients had adhered to treatment and if they had adopted any behavioral changes at 3 months and 1 year after the stroke. The algorithm was developed on the basis of the 2016 European Guidelines on cardiovascular disease prevention in clinical practice and WHO recommendations [ 19 , 20 ]. Two interviews designed to assess different aspects of lifestyle and behavioral changes were conducted ( Figure 2 ).…”

Section: Methodsmentioning

confidence: 99%

Influence of Pain and Discomfort in Stroke Patients on Coping Strategies and Changes in Behavior and Lifestyle

et al. 2021

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The implementation of prevention strategies can reduce the risk of having a stroke. This prospective, longitudinal, multicenter observational study of 82 patients describes health habits, quality of life, coping strategies, and physical and neurological status at 3 months and 1 year after stroke. The EuroQoL-5D quality of life scale (EQ-5D) and the coping strategy measurement scale (COPE-28) were used to assess pain and discomfort, and behavioral and lifestyle changes. Significant differences were observed in the pain or discomfort levels of those patients with behavioral and lifestyle changes. Correlation was also found between pain or discomfort and the coping strategies associated with active emotional support at 1 year after stroke. The results of the pain or discomfort dimension were not, however, associated with better adherence to treatment. Pain and discomfort could have a predictive value in changes in lifestyles and behaviors but not for treatment adherence in patients who have had a stroke, which is significant at 1 year. In addition to important active coping strategies such as social support, these changes in behavior and lifestyle following a stroke are long-term and should therefore be assessed during the initial examination.

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Post-stroke medication adherence and persistence rates: a meta-analysis of observational studies

Cited by 44 publications

References 47 publications

Post-stroke fatigue: a scoping review

Post-stroke fatigue: a scoping review

Evaluation of the “partnership care model” on quality of life and activity of daily living in stroke patients: A randomized clinical trial

Influence of Pain and Discomfort in Stroke Patients on Coping Strategies and Changes in Behavior and Lifestyle

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