Post-translational modifications in sepsis-induced organ dysfunction: mechanisms and implications
Lin Song,
Wei Jiang,
Hua Lin
et al.
Abstract:As a grave and highly lethal clinical challenge, sepsis, along with its consequent multiorgan dysfunction, affects millions of people worldwide. Sepsis is a complex syndrome caused by a dysregulated host response to infection, leading to fatal organ dysfunction. An increasing body of evidence suggests that the pathogenesis of sepsis is both intricate and rapid and involves various cellular responses and signal transductions mediated by post-translational modifications (PTMs). Hence, a comprehensive understandi… Show more
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