Post Transplant Diabetes Mellitus in Ahmed Gasim Kidney Transplant Center, Sudan

El-Magzoub, A-A; Elamin, Sarra

doi:10.4314/ajnt.v1i1.58816

Cited by 1 publication

(2 citation statements)

References 21 publications

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“…The results of the present study concur with a retrospective study of 221 Sudanese patients who received live donor kidney transplantation in Ahmed Gasim Kidney Transplant Center between December 2001 and December 2007, in which the reported 12-month cumulative incidence of PTDM in the transplant population was 17.6% [ 9 ]. Similarly, in a study in Japan, where 127 post-transplant patients were followed up, the incidence rate of PTDM was 15.1% in Japanese kidney transplant recipients [ 16 ].…”

Section: Discussionsupporting

confidence: 90%

“…A number of large studies compared the cumulative incidence of PTDM in tacrolimus and cyclosporinetreated patients and showed that tacrolimus was associated with a higher relative risk of PTDM when compared to cyclosporine [8][9][10]. Studies have reported an incidence of 4.7% in patients receiving cyclosporine versus 11.5% of those on tacrolimus-based immunosuppression, post-renal transplant [10].…”

Section: Need For Studymentioning

confidence: 99%

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Post-transplant Diabetes Mellitus in Kidney Transplant Recipients in Sudan: A Comparison Between Tacrolimus and Cyclosporine-Based Immunosuppression

Yousif¹,

Abdelwahab²

2022

Cureus

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Hyperglycemia is a common complication among transplant patients without a history of diabetes mellitus (DM). Although new and potent immunosuppressants have improved short and long-term outcomes after transplantation, these drugs themselves may be associated with a greater risk of hyperglycemia. The present study aimed to determine the prevalence of post-transplant diabetes mellitus (PTDM) in post renal transplant patients in Sudan, and compare the effect of cyclosporine and tacrolimus-based immunosuppressive regimens. All adult kidney transplant recipients without pre-transplant diabetes who attended the transplant clinic at Ahmed Gasim Cardiac Surgery and Renal Transplant Center in Sudan were included. A total of 100 cases with functioning kidney allografts were enrolled in this study. The majority of cases were in the age range between 20 and 60 years (92%). Males and females were nearly equally distributed (56% vs 44%). Fifty-two percent of patients were on cyclosporine and 48% on tacrolimus. Overall, 18% of patients suffered from post-transplant diabetes mellitus. There was no statistically significant difference between tacrolimus and cyclosporine with regards to the prevalence of hyperglycemia (16.6% versus 13.4%; p>0.05).

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Section: Discussionsupporting

confidence: 90%

Section: Need For Studymentioning

confidence: 99%

Post-transplant Diabetes Mellitus in Kidney Transplant Recipients in Sudan: A Comparison Between Tacrolimus and Cyclosporine-Based Immunosuppression

Yousif¹,

Abdelwahab²

2022

Cureus

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Post Transplant Diabetes Mellitus in Ahmed Gasim Kidney Transplant Center, Sudan

Abstract: Introduction: New onset post transplant diabetes mellitus (PTDM) is a common complication of kidney transplantation with a negative impact on patient and graft survival. Non-white ethnicity is a well known risk factor for PTDM.

Cited by 1 publication

References 21 publications

Post-transplant Diabetes Mellitus in Kidney Transplant Recipients in Sudan: A Comparison Between Tacrolimus and Cyclosporine-Based Immunosuppression

Post-transplant Diabetes Mellitus in Kidney Transplant Recipients in Sudan: A Comparison Between Tacrolimus and Cyclosporine-Based Immunosuppression

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