Post typhoid fever neuroretinitis with serous retinal detachment and choroidal involvement-A case report

Khatri, Anadi; Wagle, Bivek; Hony, K.C.; Chaurasiya, Babu Dhanendra; Timalsena, Satish; Singh, Kinsuk; Agrawal, Rupesh

doi:10.1016/j.ajoc.2021.101025

Cited by 2 publications

(2 citation statements)

References 16 publications

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“…CT returned to normal levels following systemic steroid therapy with oral ciprofloxacin in this case. [ 23 ]…”

Section: Discussionmentioning

confidence: 99%

Choroidal and central macular thickness before and after treatment in post fever retinitis

Sanjay,

Acharya,

Kawali

et al. 2024

Indian Journal of Ophthalmology

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Purpose: To study the choroidal thickness (CT) and central macular thickness (CMT) in post-fever retinitis (PFR) and their correlation with visual acuity and treatment. Methods: A retrospective, observational study of patients presenting with PFR from 2013 to 2021 and with spectral domain optical coherence tomography (SD-OCT) (Heidelberg®, SpectralisTM, Heidelberg, Germany) images were included. The CT and CMT were measured at presentation and at the final visit. The CT was measured subfoveally and at points 2000 µm superior, inferior, medial, and lateral from the fovea using the caliper tool. Results: Seventy-nine eyes of 65 patients were included for this study. The mean age was 39.03 (±16.00) years with female preponderance of 53.84% (n = 35). Mean follow-up duration was 30 days. Mean CT at presentation and at follow-up was 254.12 µm and 241.51 µm, respectively. CT was decreased in majority of the eyes 67.1% (n = 53) from their baseline value. Mean CMTs at presentation and final visit were 454.8 µm and 223.7 µm, respectively. Best corrected visual acuity had a positive correlation with CMT (r = 0.340; P = 0.002) and negligible correlation with CT. A significant decrease in the mean CT was noted in patients who received doxycycline either alone or in combination with a steroid as compared to those who did not receive any treatment (P < 0.001). The significance of which is unknown presently. Conclusion: CMT has a greater role in determining the final visual outcome than CT. CT can be reduced post-treatment with no effect on vision.

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“…CT returned to normal levels following systemic steroid therapy with oral ciprofloxacin in this case. [ 23 ]…”

Section: Discussionmentioning

confidence: 99%

Choroidal and central macular thickness before and after treatment in post fever retinitis

Sanjay,

Acharya,

Kawali

et al. 2024

Indian Journal of Ophthalmology

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“…Choroidal imaging showed abnormal “patchy” flow voids in the choriocapillaris-likely suggestive of a sluggish blood flow or ischemia. Deep range imaging (DRI) of the choroid revealed increased choroidal thickness and dilated choroidal vasculature, indicating a concurrent choroidal inflammation 23 .…”

Section: Discussionmentioning

confidence: 99%

Optical coherence tomography angiography (OCTA) of retinal vasculature in patients with post fever retinitis: a qualitative and quantitative analysis

Sanjay

Gadde

Agrawal

et al. 2021

Sci Rep

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Post fever retinitis is a heterogenous entity that is seen 2–4 weeks after a systemic febrile illness in an immunocompetent individual. It may occur following bacterial, viruses, or protozoal infection. Optical coherence angiography (OCTA) is a newer non-invasive modality that is an alternative to fundus fluorescein angiography to image the retinal microvasculature. We hereby describe the vascular changes during the acute phase of post fever retinitis on OCTA. Imaging on OCTA was done for all patients with post fever retinitis at presentation with 3 × 3 mm and 8 × 8 mm scans centred on the macula and corresponding enface optical coherence tomography (OCT) scans obtained. A qualitative and quantitative analysis was done for all images. 46 eyes of 33 patients were included in the study. Salient features noted were changes in the superficial (SCP) and deep capillary plexus (DCP) with capillary rarefaction and irregularity of larger vessels in the SCP. The DCP had more capillary rarefaction when compared to the SCP. The foveal avascular zone (FAZ) was altered with an irregular perifoveal network. Our series of post fever retinitis describes the salient vascular features on OCTA. Although the presumed aetiology was different in all our patients, they developed similar changes on OCTA. While OCTA is not useful if there is gross macular oedema, the altered FAZ can be indicative of macular ischemia.

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Post typhoid fever neuroretinitis with serous retinal detachment and choroidal involvement-A case report

Cited by 2 publications

References 16 publications

Choroidal and central macular thickness before and after treatment in post fever retinitis

Choroidal and central macular thickness before and after treatment in post fever retinitis

Optical coherence tomography angiography (OCTA) of retinal vasculature in patients with post fever retinitis: a qualitative and quantitative analysis

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