Post-vaccination antibodies profile against Peste des petits ruminants (PPR) virus in sheep and goats of Punjab, Pakistan

Khan, Haider Ali; Siddique, M.; Arshad, Muhammad; Abubakar, Muhammad; Akhtar, Masood; Arshad, Muhammad; Ashraf, Muhammad

doi:10.1007/s11250-008-9222-6

Cited by 24 publications

(29 citation statements)

References 14 publications

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“…In another study the case fatality rates were 46.9% and 34.4% in goat and sheep populations affected by PPRV, respectively (Shankar et al, 1998). This observation is consistent with the previous reports of Khan et al, 2007 andAbubaker et al (2008) who reported that the PPR disease outbreaks were more severe in goats than sheep. The increased severity of PPRV infection in goats than sheep could be attributed to marked immunosuppression in infected goats (Rajak et al, 2005) that occurred through inhibition of leukocyte proliferation (Heaney et al, 2002), apoptosis of peripheral blood mononuclear cells (Mondal et al, 2001) and/or downregulation of CD46 (Galbraith et al, 1998).…”

Section: Discussionsupporting

confidence: 94%

Emergence of peste des petits ruminants virus lineage IV in Ismailia Province, Egypt

Soltan

Abd-Eldaim

2014

Infection, Genetics and Evolution

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Section: Discussionsupporting

confidence: 94%

Emergence of peste des petits ruminants virus lineage IV in Ismailia Province, Egypt

Soltan

Abd-Eldaim

2014

Infection, Genetics and Evolution

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“…The odds of being seropositive were 1.06 (95% CI 0.89-1.25) in goats than in sheep, which implies there is no difference between the species. This is in contradiction with some studies, including one carried out in Tanzania [11], which reported a higher seroprevalence in goats than in sheep and linked it to higher fecundity in goats compared to sheep [2,18,22]. Other studies have reported higher seroprevalence in sheep than goats, attributing it to lower number of sheep sampled or due to the fact that goats are often affected more severely by the disease hence die prior to sampling [19,23].…”

Section: Discussionmentioning

confidence: 85%

Seroprevalence of Peste Des Petits Ruminants Virus from Samples Collected in Different Regions of Tanzania in 2013 and 2015

Kgotlele¹,

Torsson²,

Kasanga³

2016

J Vet Sci Technol

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Sero-surveillance was conducted to determine seroprevalence of peste des petits ruminant's virus (PPRV) in sheep and goats population of Tanzania using samples collected in 2013 and 2015. A total of 3,838 samples were collected from villages in 14 of the 25 mainland regions. Samples were tested by competitive ELISA for detection of antibodies against PPRV. Overall, 998 of the samples were found to be positive for antibodies against PPR, giving a seroprevalence of 27.1%. In this study, there was no statistical significant difference of getting PPR between sheep and goats (odds ratio of 1.06, 95% CI 0.89-1.25). The overall seroprevalence indicates that PPR is prevalent in small ruminants in the study areas. The study also confirms the presence of antibodies against PPR in sheep and goats in regions of Tanzania that previously had little to no data on the disease, an indication that PPR is spreading within Tanzania with the possibility of spreading to neighboring countries.

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“…The small ruminants play an important role in sustainable agriculture and for poverty alleviation in the country. The existence of PPR has been recognized in Pakistan since 1991 on the basis of clinical signs (Pervez et al, 1993;Athar et al, 1995;Amjad et al, 1996 andTahir et al, 1998) and on the basis of laboratory confirmation (Khan et al, 2007;Abubakar et al, 2008).…”

Section: Introductionmentioning

confidence: 99%

Evidence of Peste des Petits Ruminants in Serology of Sheep and Goats from Sindh, Pakistan

Abubakar¹,

Arshed²,

Hussain

et al. 2010

Transboundary and Emerging Diseases

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The following is the first detailed description of laboratory confirmed evidence of peste des petits ruminant virus (PPRV) in 14 districts of Sindh province, Pakistan. Sindh is the 2nd largest province of Pakistan in terms of human population and livestock. Livestock are the main origin of the people's livelihood. Samples were collected during the surveillance programme from sheep and goats showing severe respiratory signs and mouth lesions. Competitive enzyme-linked immuno-sorbant assay (cELISA) was performed to detect the presence of antibodies in the serum against PPRV. Findings suggested that the overall PPR sero-prevalence in sheep was 49.5% when compared to goats, which was 56.3%. As we observed during an 18 months' period, most of the cases that occurred emerged with the start of hot season and peaked during the months of April, May, June and July, and then the prevalence dropped. Among various age groups, the animals that showed the higher prevalence of antibodies to PPRV were >2 years. In the age group <1 year, there was a significant difference in the prevalence which was 48.6% in goats when compared to 32.1% in sheep. Similarly, it was the same in the second age group (1-2 years), 46.9% in sheep when compared to 55.3% goats. There was little variation in the third age group (>2 years), being around 61.7% in goats when compared to 63.4% in sheep. The highest sero-prevalence was in Tharparkar followed by Mirpur Khas and Tando Allahyar. The study indicated the scenario of PPRV circulation in the population of the two domestic ruminant species (sheep and goats) with frequent disease outbreaks.

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Post-vaccination antibodies profile against Peste des petits ruminants (PPR) virus in sheep and goats of Punjab, Pakistan

Cited by 24 publications

References 14 publications

Emergence of peste des petits ruminants virus lineage IV in Ismailia Province, Egypt

Emergence of peste des petits ruminants virus lineage IV in Ismailia Province, Egypt

Seroprevalence of Peste Des Petits Ruminants Virus from Samples Collected in Different Regions of Tanzania in 2013 and 2015

Evidence of Peste des Petits Ruminants in Serology of Sheep and Goats from Sindh, Pakistan

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