2020
DOI: 10.1007/s00394-020-02438-3
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Post-weight loss changes in fasting appetite- and energy balance-related hormone concentrations and the effect of the macronutrient content of a weight maintenance diet: a randomised controlled trial

Abstract: Purpose We investigated the effects of the macronutrient composition of diets with differing satiety values on fasting appetite-related hormone concentrations after weight loss and examined whether the hormone secretion adapted to changes in body fat mass (FM) and fat-free mass (FFM) during the weight maintenance period (WM). Methods Eighty-two men and women with obesity underwent a 7-week very-low-energy diet (VLED) and were then randomised to a higher-sa… Show more

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Cited by 11 publications
(14 citation statements)
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“…Similarly, a 20% higher protein intake (18 vs. 15% of energy as protein) during weight maintenance caused higher sensations of satiety and a 50% lower weight regain 3 months after weight loss (23). However, in line with our findings, a recent trial, published in 2020, showed that two isoenergetic weight-maintenance diets that differed in protein, fiber, and fat content (a "higher-satiety diet" vs. a "lower-satiety diet") were no different from each other in terms of effects on fasting gut hormone concentrations (31). A reason that may explain the discrepancy in findings might be the absolute protein content of the weight-maintenance diets (22) and differences in compliance (32).…”
Section: Discussionsupporting
confidence: 91%
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“…Similarly, a 20% higher protein intake (18 vs. 15% of energy as protein) during weight maintenance caused higher sensations of satiety and a 50% lower weight regain 3 months after weight loss (23). However, in line with our findings, a recent trial, published in 2020, showed that two isoenergetic weight-maintenance diets that differed in protein, fiber, and fat content (a "higher-satiety diet" vs. a "lower-satiety diet") were no different from each other in terms of effects on fasting gut hormone concentrations (31). A reason that may explain the discrepancy in findings might be the absolute protein content of the weight-maintenance diets (22) and differences in compliance (32).…”
Section: Discussionsupporting
confidence: 91%
“…Indeed, the moderate protein group in our study showed a protein intake above 0.8 g per kg of body weight, compared with 0.6 g per kg body weight in other studies (22,23,26). Similarly, in the recent study mentioned above (31), the percent of energy intake as protein was also around 17% in both groups, equivalent to ∼0.8 g per kg of body weight, based on average pre-weight-loss body weights. According to Soenen et al (22), a dietary protein intake of 0.8 g per kg of body weight is sufficient for body weight maintenance.…”
Section: Discussionsupporting
confidence: 54%
“…In addition, the participants were allowed to consume ad libitum low-energy vegetables and noncaloric beverages (21). The detailed study design has been previously described (21,22). For the analyses, 78 subjects who enrolled in both the baseline and post-weight loss phase were included (21 men and 57 women, age 49.9 ± 8.9 years, BMI 34.2 ± 2.6 kg/m 2 ).…”
Section: Methodsmentioning
confidence: 99%
“…The clinical measurements in KOBS (20) and ELIPA (22) have been described in detail before. BMI was calculated as weight (in kilograms) divided by height squared (in meters).…”
Section: Clinical Measurements and Laboratory Determinationsmentioning
confidence: 99%
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