Postaerobic Exercise Blood Pressure Reduction in Very Old Persons With Hypertension

Oliveira, Joana; Mesquita-Bastos, José; Melo, Cristina; Ribeiro, Fernando

doi:10.1519/jpt.0000000000000049

Cited by 14 publications

(14 citation statements)

References 34 publications

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“…The antihypertensive effects of exercise include the improvement of exercise tolerance, peripheral perfusion, arterial stiffness, autonomic function, endothelial repair, among others [168-172]. Indeed, exercise can produce clinical benefits in resistant hypertension [173] and, even in an old age group, exercise training could be an important nonpharmacological strategy [174]. Among the disparate aspects of mechanisms through which blood pressure control is improved by exercise, endothelial function, SMC phenotype switching and peripheral capillary rarefaction will be discussed in terms of their potential relationship with miRNAs (Figure 2).…”

Section: Potential Role Of Mirnas In Therapy and Prognostic For Hypermentioning

confidence: 99%

Mechanisms and therapeutic potential of microRNAs in hypertension

Shi

Liao

Liu

et al. 2015

Drug Discovery Today

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Hypertension is the major risk factor for the development of stroke, coronary artery disease, heart failure and renal disease. The underlying cellular and molecular mechanisms of hypertension are complex and remain largely elusive. MicroRNAs (miRNAs) are short, noncoding RNA fragments of 22–26 nucleotides and regulate protein expression post-transcriptionally by targeting the 3′-untranslated region of mRNA. A growing body of recent research indicates that miRNAs are important in the pathogenesis of arterial hypertension. Herein, we summarize the current knowledge regarding the mechanisms of miRNAs in cardiovascular remodeling, focusing specifically on hypertension. We also review recent progress of the miRNA-based therapeutics including pharmacological and nonpharmacological therapies (such as exercise training) and their potential applications in the management of hypertension.

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Section: Potential Role Of Mirnas In Therapy and Prognostic For Hypermentioning

confidence: 99%

Mechanisms and therapeutic potential of microRNAs in hypertension

Shi

Liao

Liu

et al. 2015

Drug Discovery Today

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“…The participants mostly belonged to the older age group (65-79). In the study carried out by Ho et al (2012), the participants belonged to the middle-aged group (40-64) and in the study of Oliveira et al, (2016) to the very old group (>80) according to the division of ACSM. In the research conducted by Thiebaud et al (2016) all age groups were included, and for this review, only the age group that met the criterion was taken into consideration.…”

Section: Study Characteristicsmentioning

confidence: 99%

“…In the research conducted by Thiebaud et al (2016) all age groups were included, and for this review, only the age group that met the criterion was taken into consideration. Gender-wise, women were the more represented group, with 13 studies including only female participants, five including both sexes (de Freitas Heffernan et al, 2013;Ho et al, 2012;Oliveira et al, 2016;Yasuda et al, 2014), whereas in three studies the participants were only male (Kawano et al, 2012;Lacombe et al, 2011;Thiebaud et al, 2016). In 15 analyzed studies, the participants had a previous history of prehypertension, in four studies participants had a previous history of hypertension (Brito et al, 2014;de Freitas Brito et al, 2014;Kawano et al, 2012;Yasuda et al, 2014) and two studies contained a sample of normotensive and prehypertensive participants (Gomes, Almeida, Silva, & Becker, 2011;Ubolsakka-Jones et al, 2016).…”

Section: Study Characteristicsmentioning

confidence: 99%

“…The influence of resistance training (RT) on blood pressure was examined in 12 studies, while the influence of AT was examined in six of them (Cunha & Jardim, 2012;Cunha et al, 2017;Gomes et al, 2011Gomes et al, , 2016Lacombe et al, 2011;Oliveira et al, 2016) and three studies focused on their combination (Ho et al, 2012;Kawano et al, 2012;Ubolsakka-Jones et al, 2016). Experimental programs ranged from one training (14 studies), eight-and 12-week training programs (Ho et al, 2012), 12-week training programs (Heffernan et al, 2013;Terra et al, 2008;Yasuda et al 2014), four-month training programs (Mota et al, 2013) and five-month training programs (Jefferson et al, 2015).…”

Section: Study Characteristicsmentioning

confidence: 99%

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Effects of Different Types of Exercise Programs on Arterial Blood Pressure of the Elderly

Petrović

Marinković

2019

FU Phys Ed Sport

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The value of arterial blood pressure is variable. It depends on the time of the day, external and internal factors such as genetics and lifestyle. Moderate and regular physical activity, as well as weight reduction, can affect the reduction of high arterial blood pressure (ABP). The influence of physical activity on the health of the elderly is not well researched. The objective of this systematic review study is to collect and analyze studies of the effects of different types of exercise programs on arterial blood pressure of the elderly. Based on an analysis of electronic databases and the inclusion criteria set, 21 studies were included in the analysis. Performing only one exercise training program with the elderly leads to a fall of systolic blood pressure (SBP) from 7 to 30 mm Hg and of diastolic blood pressure (DBP) from 3 to 17 mm Hg, whereas a long term training program reduces SBP for 17 and DBP for 7mm Hg. The combination of aerobic training (AT) and resistance training (RT) with the elderly gives the best results in reducing ABP, increasing arterial elasticity, thus reducing the chance of getting a cardiovascular disease.

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“…PEH is considered a prolonged decrease in resting blood pressure in the minutes and hours (up to 24 h) after an acute bout of exercise [13]. This decrease is more pronounced in hypertensive patients [14] and has also been shown in very old adults [15].…”

Section: Benefits Of Continuous Aerobic Training For Hypertensionmentioning

confidence: 99%

Exercise for Hypertension

Chulvi‐Medrano¹,

José²,

Tortosa-Martínez³

et al. 2016

Fitness Medicine

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High blood pressure (HBP) does not cause discomfort but still, you need to take care of and treat it. Otherwise, over time, it can damage the heart, kidneys, brain, and eyes. Lifestyle changes are essential in HBP, and physical activity is a parameter of great influence. In order to achieve the benefits derived from physical activity, it must be adequately prescribed, an aspect that will be developed in this chapter. The first section addresses the physiopathology of hypertension, with special interest in the pathological mechanisms that may induce hypertension, devices for monitoring blood pressure (BP), and an overview of the particularities that present hypertension in the presence of other pathologies and over the life span. Second section focuses on exercise prescription for hypertensive people, exploring each type of exercise that has been proved to be effective. We discuss for each type of exercise, the benefits, mechanisms involved in these benefits, the appropriate dose of exercise, and other methodological considerations including risk management issues. We conclude with a clinical case study. A detailed exercise training program will be developed for this particular case study in order to try to bridge the gap between theory and practice.

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Postaerobic Exercise Blood Pressure Reduction in Very Old Persons With Hypertension

Cited by 14 publications

References 34 publications

Mechanisms and therapeutic potential of microRNAs in hypertension

Mechanisms and therapeutic potential of microRNAs in hypertension

Effects of Different Types of Exercise Programs on Arterial Blood Pressure of the Elderly

Exercise for Hypertension

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