Postauricular Melanocytic Neuroectodermal Tumor of Infancy: A Rare Site of a Rare Tumor—MNTI as a Postauricular Mass with Literature Review

Evans, Sean; Woolley, Audie L.

doi:10.1155/2018/9829856

Cited by 2 publications

(2 citation statements)

References 8 publications

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“…More than 500 cases of MNTI have been reported worldwide by Rachidi et al In addition to the 472 cases reported between 1918 and 2013 as a part of the largest retrospective study, [5] we found 49 cases reported between January 2014 and June 2021 by searching PubMed [3,4,9–32,36–38] . In a systematic review of 472 MNTI cases, [5] most cases developed within 1 year of age, with more than 90% of cases occurring in the craniofacial region, such as the maxilla (60.3%), skull (18.1%), and mandible (10.3%).…”

Section: Discussionmentioning

confidence: 75%

Melanotic neuroectodermal tumor of infancy in the mandible

et al. 2021

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Rationale: Melanocytic neuroectodermal tumor of infancy (MNTI) is a rare benign pigmented neoplasm that arises from the neural crest and has an aggressive growth pattern. It is predominantly seen in infants under 1 year of age, and the most common site of involvement is the maxilla. The currently accepted treatment is removal by surgical resection. Herein, we report a case of MNTI that involved the anterior alveolar ridge of the mandible in a 6-month-old infant. Patient concerns: A case of a 6-month-old male child with a huge mass in the anterior alveolar ridge of the mandible. Diagnosis: The tumor was diagnosed using histopathological and immunohistochemical techniques on the biopsy specimen obtained following incisional biopsy. Based on the findings, a final diagnosis of MNTI was established. Interventions: Radical resection of the tumor was performed, after determining the extent of resection by referring to the mandibular 3D model created using the pre-operative CT data. Outcomes: The postoperative course was uneventful, and no recurrence has been observed to date for more than 4 years after surgery. Lessons: This case emphasizes that early diagnosis and radical surgery are critical to the effective treatment, as MNTI exhibits rapid and destructive growth. It also requires careful and close follow-up because of high recurrence rates.

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Section: Discussionmentioning

confidence: 75%

Melanotic neuroectodermal tumor of infancy in the mandible

et al. 2021

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“…Other reported sites of origin include the central nervous system, mediastinum, uterus, epididymis, ovary, testes, upper arm, thigh, post auricular subcutaneous tissue and skin [3,[17][18][19][20][21]. Malignant change can occur and has been reported to range from 1.9% -6.5% of cases.…”

Section: Discussionmentioning

confidence: 99%

A Case Report on Melanotic Neuroectodermal Tumor of Infancy and Review of the Literature

Jugmohansingh¹,

Medford²,

Sharma³

et al. 2020

AJSCR

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Melanotic neuroectodermal tumor of infancy (MNTI) is a rare, benign neoplasm of neural crest origin that most commonly occurs in the first year of life. The craniofacial area is affected 90% of the time with the maxilla being the affected site in the majority of cases. It has a recurrence rate of up to 27% and is associated with malignant transformation in up to 6.5% of patients. The current case describes the clinical presentation and management of a 3-month old male infant with MNTI of the maxilla. Following initial presentation, the tumor grew rapidly to compromise the aerodigestive tract. Surgical resection was performed and the adjacent bone was burred. There has been no clinical recurrence over a 4-year period of follow up.

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Postauricular Melanocytic Neuroectodermal Tumor of Infancy: A Rare Site of a Rare Tumor—MNTI as a Postauricular Mass with Literature Review

Cited by 2 publications

References 8 publications

Melanotic neuroectodermal tumor of infancy in the mandible

Melanotic neuroectodermal tumor of infancy in the mandible

A Case Report on Melanotic Neuroectodermal Tumor of Infancy and Review of the Literature

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