Postcardiac Injury Syndrome Following Transvenous Pacer or Defibrillator Insertion: CT Imaging and Review of the Literature

Wolk, Ben; Dandes, Eric; Martinez, Felipe; Helguera, Marcelo E.; Pinski, Sergio L.; Kirsch, Jacobo

doi:10.1067/j.cpradiol.2012.12.001

Cited by 14 publications

(13 citation statements)

References 18 publications

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“…; Wolk et al. ). Novel approaches to control cardiac function are now possible with gene therapy or a combination of gene therapy and regulated gene expression (Lee et al.…”

Section: Introductionmentioning

confidence: 98%

Optogenetic stimulation of Drosophila heart rate at different temperatures and Ca²⁺ concentrations

et al. 2016

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Optogenetics is a revolutionary technique that enables noninvasive activation of electrically excitable cells. In mammals, heart rate has traditionally been modulated with pharmacological agents or direct stimulation of cardiac tissue with electrodes. However, implanted wires have been known to cause physical damage and damage from electrical currents. Here, we describe a proof of concept to optically drive cardiac function in a model organism, Drosophila melanogaster. We expressed the light sensitive channelrhodopsin protein ChR2.XXL in larval Drosophila hearts and examined light‐induced activation of cardiac tissue. After demonstrating optical stimulation of larval heart rate, the approach was tested at low temperature and low calcium levels to simulate mammalian heart transplant conditions. Optical activation of ChR2.XXL substantially increased heart rate in all conditions. We have developed a system that can be instrumental in characterizing the physiology of optogenetically controlled cardiac function with an intact heart.

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“…; Wolk et al. ). Novel approaches to control cardiac function are now possible with gene therapy or a combination of gene therapy and regulated gene expression (Lee et al.…”

Section: Introductionmentioning

confidence: 98%

Optogenetic stimulation of Drosophila heart rate at different temperatures and Ca²⁺ concentrations

et al. 2016

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“…Post-pacemaker insertion pericarditis is a rare form of PCIS with an estimated incidence of 1 to 2% after pacer implantation. 4 The mechanism of PCIS in general and post pacemaker insertion pericarditis in particular is still not well understood.…”

Section: Discussionmentioning

confidence: 99%

“…In rare occasions, lead perforation maybe visible on imaging studies. 4 Early diagnosis of pacemaker induced PCIS is very important as most of these patients respond well to medical treatment with NSAID, colchicine and/or steroids. 7 Although PCIS typically has a benign course, it may result in significant morbidity and mortality due to cardiac tamponade, arrhythmias and pulmonary edema.…”

Section: Discussionmentioning

confidence: 99%

Pacemaker Induced Post Cardiac Injury Syndrome

Ayan¹

2015

MOJCR

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Post pacemaker insertion pericarditis is a rare form of post cardiac injury syndrome. It is an inflammatory process involving the pericardium and/or pleura due to a recent cardiac injury. Post cardiac injury syndrome may develop after myocardial infarction (Dressler syndrome), cardiac surgery or trauma. However, in rare cases it can occur following minor cardiac procedures. We report a case of a 74-year-old male with post-cardiac injury syndrome 4weeks post permanent pacemaker implantation. A high index of suspicion in addition to ordering appropriate imaging studies and device interrogation are crucial to establish correct diagnosis and rule out lead perforation.

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“…This hypothesis is strengthened by the observations that only leads placed on the lateral or anterolateral wall seem to provoke acute pericarditis [137] and that active-fixation leads seem crucial for the development of the disease [40,41]. Direct irritation of the pericardium by slightly protruding electrodes might be another possible trigger for the inflammatory response [40,41,138]. Hemopericardium is also a rare but possible complication of percutaneous mitral balloon valvuloplasty [139].…”

Section: Other Triggers Of Ppsmentioning

confidence: 99%

Postpericardiotomy syndrome after cardiac surgery

Lehto

Kiviniemi

2020

Annals of Medicine

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Postpericardiotomy syndrome (PPS) is a well-known complication after cardiac surgery. The syndrome results in prolonged hospital stay, readmissions, and invasive interventions. Previous studies have reported inconsistent results concerning the incidence and risk factors for PPS due to the differences in the applied diagnostic criteria, study designs, patient populations, and procedure types. In recent prospective studies the reported incidences have been between 21 and 29% in adult cardiac surgery patients. However, it has been stated that most of the included diagnoses in the aforementioned studies would be clinically irrelevant. This challenges the specificity and usability of the currently recommended diagnostic criteria for PPS. Moreover, recent evidence suggests that PPS requiring invasive intervention such as the evacuation of pleural and/or pericardial effusion is associated with increased mortality. In the present review, we summarise the existing literature concerning the incidence, clinical features, diagnostic criteria, risk factors, management, and prognosis of PPS. We also propose novel approaches regarding to the definition and diagnosis of PPS. KEY MESSAGES: 1. Current diagnostic criteria of PPS should be reconsidered, and the analyses should be divided into subgroups according to the severity of the syndrome to achieve more clinically applicable and meaningful results in the future studies. 2. In contrast with the previous presumption, severe PPSdefined as PPS requiring invasive interventionswas recently found to be associated with higher all-cause mortality during the first two years after cardiac surgery. The association with an increased mortality supports the use of relatively aggressive prophylactic methods to prevent PPS. 3. The risk factors clearly increasing the occurrence of PPS are younger age, pleural incision, and valve and ascending aortic procedures when compared to CABG.

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Postcardiac Injury Syndrome Following Transvenous Pacer or Defibrillator Insertion: CT Imaging and Review of the Literature

Cited by 14 publications

References 18 publications

Optogenetic stimulation of Drosophila heart rate at different temperatures and Ca²⁺ concentrations

Optogenetic stimulation of Drosophila heart rate at different temperatures and Ca²⁺ concentrations

Pacemaker Induced Post Cardiac Injury Syndrome

Postpericardiotomy syndrome after cardiac surgery

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Postcardiac Injury Syndrome Following Transvenous Pacer or Defibrillator Insertion: CT Imaging and Review of the Literature

Cited by 14 publications

References 18 publications

Optogenetic stimulation of Drosophila heart rate at different temperatures and Ca2+ concentrations

Optogenetic stimulation of Drosophila heart rate at different temperatures and Ca2+ concentrations

Pacemaker Induced Post Cardiac Injury Syndrome

Postpericardiotomy syndrome after cardiac surgery

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Product

Resources

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Optogenetic stimulation of Drosophila heart rate at different temperatures and Ca²⁺ concentrations

Optogenetic stimulation of Drosophila heart rate at different temperatures and Ca²⁺ concentrations