Posterior Pole Retinal Thickness in Ocular Hypertension and Glaucoma

Abstract

The RTA can reveal increased hemispheric thickness asymmetries in both OHT and OAG eyes. In OAG eyes thickness asymmetries are associated with corresponding perimetric asymmetries. The findings in OHT eyes suggest that localized anatomic and functional damage to inner retina may not develop in parallel early in the disease process.

The Ability of 10-2 Short-Wavelength Perimetry in Detecting Functional Loss of the Macular Area in Preperimetric Glaucoma Patients

“…Horizontal hemifield asymmetry has been shown to be valuable in assessment of early glaucomatous changes. 24,33,34 Similarly, in our study, the relationships between GCIPL and MS asymmetries exhibited higher correlations than did direct comparisons between GCIPLT and MS.…”

Structural and functional assessment by hemispheric asymmetry testing of the macular region in preperimetric glaucoma

“…Bagga et al [17] showed that a macular thickness symmetry test had the potential to detect glaucomatous damage using TD-OCT. Salgarello et al [18] reported that hemispheric asymmetry in glaucomatous eyes increased compared with the control group using RTA. These results are in agreement with our report where macular symmetry testing values of PG eyes were significantly different from those of control eyes using SD-OCT measurements.…”

“…Meanwhile, horizontal hemifield asymmetry is regarded as very useful in the assessment of early glaucomatous changes as it measures disparity in macular thickness between superior and inferior zone [17,18]. Glaucomatous damage usually commences in only one horizontal hemifield and is assessed using the glaucoma hemifield test, which measures the disparity in retinal sensitivity between the superior and inferior hemifields [19].…”

Facilitating Glaucoma Diagnosis With Intereye Retinal Nerve Fiber Layer Asymmetry Using Spectral-Domain Optical Coherence Tomography

“…RNFL thickness asymmetry can be an early sign of glaucomatous damage and has been explored by OCT technology using 2 main methods: (1) assessing RNFL thickness asymmetry between vertically opposing quadrants of the same eye 41,46,[50][51][52][53] ; and (2) assessing intereye RNFL asymmetry for global average and for quadrants and sectors. [41][42][43][44][45][46]53,54 This study focuses on asymmetry analysis using the second method and demonstrates that OAG eyes exhibit significantly greater intereye mean RNFL asymmetry compared with normal eyes (Fig.…”