Posterior quadrantic dysplasia: MRI diagnosis of a lesser known cause of pediatric intractable epilepsy

Posterior quadrantic dysplasia (PQD) is a rare cause of medically refractory seizures among the paediatric population. We are reporting a case study of a 14-year-old female child with refractory seizures with seizure onset since birth. She was diagnosed with Posterior quadrantic dysplasia in left temporo-occipito-parietal lobes on magnetic resonance imaging. Our case report highlights the diffusion tensor imaging (DTI) and tractography along with routine magnetic resonance imaging findings in a classical presentation of PQD. DTI helps in proper delineation of white matter tract abnormalities and consequently in the approach for the surgical management. It is vital for radiologists to be familiar with these imaging findings for early diagnosis and treatment of PQD.

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Hemi-Hemimegalencephaly or Posterior Quadrantic Dysplasia, a Rare Cause of Focal Epilepsy in an Otherwise Healthy Young Woman: A Case Report

Feidert¹

2020

Cureus

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Hemimegalencephaly (HME) and its more localized form-posterior quadrantic dysplasia (PQD)-are rare malformations of cortical development (MCD) that normally manifest as refractory focal epilepsy and cognitive impairment in children. We report a case study of a 19-year-old woman who presented with seizure-like symptoms to the emergency department after discontinuing her seizure treatment having fled her country. MRI revealed typical signs of PQD. This case study demonstrates how an unusual mild clinical presentation led to the late diagnosis of this rare MCD.

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Posterior quadrantic dysplasia: MRI diagnosis of a lesser known cause of pediatric intractable epilepsy

Cited by 3 publications

References 6 publications

Case 284: Posterior Quadrantic Dysplasia

Case 284: Posterior Quadrantic Dysplasia

Posterior Quadrantic Dysplasia: An Uncommon Cause of Childhood Seizures with Brief Review of Literature

Hemi-Hemimegalencephaly or Posterior Quadrantic Dysplasia, a Rare Cause of Focal Epilepsy in an Otherwise Healthy Young Woman: A Case Report

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