Posterior reversible encephalopathy syndrome with PLEDs-plus due to mesalamine

Cherian, Ajith; Soumya, CV; Iype, Thomas; Mathew, Mini; Sandeep, P; Thadam, Jessline K; Chithra, P

doi:10.4103/0976-3147.127882

Cited by 8 publications

(3 citation statements)

References 10 publications

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“…PRES has been recognized as a neurological side effect of acute BP rising and treatment with calcineurin [17]. Few cases of PRES are reported in patients with CD and UC following infliximab [17] or mesalamine [18] administration. Our patient developed PRES in the active phase of the disease, and he was not on any medication.…”

Section: Discussionmentioning

confidence: 99%

Neurological manifestations related to Crohn’s disease: a boon for the workforce

Nemati

Mehdizadeh

Salimipour

et al. 2017

Gastroenterology Report

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The neurological manifestations of Crohn’s disease and its prevalence are not well known. Here, we report five patients of confirmed Crohn’s disease with different neurological presentations. The neurological presentations include anterior ischemic optic neuropathy, myelopathy, posterior reversible encephalopathy syndrome, chronic inflammatory demyelinating polyneuropathy, and chronic axonal sensory and motor polyneuropathy. These manifestations should be kept in mind in the assessment of Crohn’s disease.

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Section: Discussionmentioning

confidence: 99%

Neurological manifestations related to Crohn’s disease: a boon for the workforce

Nemati

Mehdizadeh

Salimipour

et al. 2017

Gastroenterology Report

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“…Inflammation declines with drug withdrawal, which is recommended, and the use of topical corticosteroids may be necessary to complete the remission of the inflammatory condition[ 38 , 72 ]. Furthermore, neurological side effects from drug therapy can cause visual impairment without directly affecting the eyes[ 126 ].…”

Section: Ocular Involvementmentioning

confidence: 99%

Ophthalmic manifestations in patients with inflammatory bowel disease: A review

Troncoso

Biancardi

Moraes

et al. 2017

WJG

112

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Clinical manifestations of inflammatory bowel disease (IBD) are not locally restricted to the gastrointestinal tract, and a significant portion of patients have involvement of other organs and systems. The visual system is one of the most frequently affected, mainly by inflammatory disorders such as episcleritis, uveitis and scleritis. A critical review of available literature concerning ocular involvement in IBD, as it appears in PubMed, was performed. Episcleritis, the most common ocular extraintestinal manifestation (EIM), seems to be more associated with IBD activity when compared with other ocular EIMs. In IBD patients, anterior uveitis has an insidious onset, it is longstanding and bilateral, and not related to the intestinal disease activity. Systemic steroids or immunosuppressants may be necessary in severe ocular inflammation cases, and control of the underlying bowel disease is important to prevent recurrence. Our review revealed that ocular involvement is more prevalent in Crohn’s disease than ulcerative colitis, in active IBD, mainly in the presence of other EIMs. The ophthalmic symptoms in IBD are mainly non-specific and their relevance may not be recognized by the clinician; most ophthalmic manifestations are treatable, and resolve without sequel upon prompt treatment. A collaborative clinical care team for management of IBD that includes ophthalmologists is central for improvement of quality care for these patients, and it is also cost-effective.

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“…Когда пациентка пришла в сознание и зрение восстановилось, отмеча-лась также нормализация ЭЭГ. Авторы сделали вывод о том, что при выявлении паттерна PLEDs на ЭЭГ по-казано внутривенное (в / в) введение антиэпилептиче-ского препарата [9]. Сходный случай описан S. H. Mittal и соавт.…”

Section: Ch I Ld Neurology R U S S I a N J O U R N A L O Funclassified