Posterior urethral valves (PUV) diagnosis and management remain a major challenge in developing countries. We sought to review cases of PUV managed in our health centre and to highlight the challenges in its management. Methods: A retrospective analysis of patients with PUV managed over a 12month period. Data obtained from patients' medical records include: demography, clinical presentation, serum electrolytes, urea and creatinine, radiological diagnosis, initial management, surgical management and the outcome of management. Results: Eight patients were managed during the period under review. The median age was 26 months. The commonest clinical feature was recurrent fever. Three patients (37.5%) had renal insufficiency requiring peritoneal dialysis at initial presentation. Six patients (75%) had Mohan's valvotomy while two (25%) died before valve ablation. One patient (12.5%) died a month after valve ablation from renal failure, while one (12.5%) had residual valve requiring a repeat valve ablation. Post-operative complication of urosepsis occurred in two patients (25%). Conclusions: Physicians should have a high index of suspicion for PUV in boys who present with recurrent fever or urinary tract infections. Screening for foetal anomalies during routine antenatal maternal ultrasonography will improve prenatal diagnosis of this condition.