Postherpetic Trigeminal Neuralgia of the V2 Branch Treated with Electrodes Placed through the Foramen Ovale: A Case Report

Abstract

Varicella zoster virus (VZV) is a DNA virus that causes both primary and recurrent viral infections. Herpes zoster (HZ), also known as shingles, is a unique condition that is induced by VZV reactivation. Neuropathic pain, malaise, and sleep disruption are prodromal symptoms in such cases. Postherpetic trigeminal neuralgia is neuropathic pain caused by varicella-zoster virus (VZV) infection of the trigeminal ganglion or branches, which remains or reappears after herpes crusting. In this report, we present a case of trigeminal neuralgia of the V2 branch after herpes, exhibiting typical findings of unusual involvement of the trigeminal nerve. Notably, the patient was treated using electrodes placed through the foramen ovale.

Varicella‐zoster virus‐related neurological complications: From infection to immunomodulatory therapies

“…122 In addition, the inflammatory response is made worse and chronic pain in PHN is maintained by the migration of immune cells, such as T cells and macrophages, to the site of VZV reactivation. 123 To manage PHN, a variety of non-pharmacological and pharmaceutical methods are often used to lessen discomfort and enhance the quality of life for those who are impacted. 124 The intensity and length of post-HZV may be decreased by antiviral medication, such HAKAMI ET AL.…”

“…Even after the initial rash has subsided, this ongoing inflammatory condition may cause cerebral sensitisation and subsequent chronic pain 122 . In addition, the inflammatory response is made worse and chronic pain in PHN is maintained by the migration of immune cells, such as T cells and macrophages, to the site of VZV reactivation 123 …”