1987
DOI: 10.1016/b978-0-12-035413-9.50007-8
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Postimplantation Defects in Development following Ionizing Irradiation

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Cited by 32 publications
(6 citation statements)
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“…Although the basis of the differing organ radio-sensitivities cannot be completely explained at present, the radio-sensitivity of different cell types may differ between γ-rays and heavy ions. Our present data suggest that embryonic development in animals is not necessarily dependent on LET and ion species, although it is reported that the postnatal development of animals is dependent on LET and heavy ion species [3]. …”
Section: Discussionmentioning
confidence: 54%
“…Although the basis of the differing organ radio-sensitivities cannot be completely explained at present, the radio-sensitivity of different cell types may differ between γ-rays and heavy ions. Our present data suggest that embryonic development in animals is not necessarily dependent on LET and ion species, although it is reported that the postnatal development of animals is dependent on LET and heavy ion species [3]. …”
Section: Discussionmentioning
confidence: 54%
“…Loss, replacement, and spatial reorganization of proliferating cells have been regarded as one of the most important mechanisms of teratogenesis and, therefore, have been the subject of numerous studies. Compensation responses and cell-cycle modification as the consequence of compensatory cell proliferation have been shown in some irradiated embryonal tissues (literature cited in [34]). These previous observations have been based mainly on histological or cytological studies.…”
Section: Possible Mechanism Of Malformation Induced By Ionizing Irradmentioning
confidence: 99%
“…In particular, Konermann (1986Konermann ( , 1987Konermann ( , 1989 has described a linear dose-response relationship for the effects of X-rays on various indices of neuronal development and maturation of the cerebral cortex and hippocampus of the albino inbred mouse, and for reductions in the diameter of the fimbria hippocampi and other structures following irradiation at between 0-05 and 1 . 0 Gy on day 13 pc .…”
Section: Discussionmentioning
confidence: 98%