Postmenopausal Hypertension and Sodium Sensitivity

Kim, Jun Mo; Kim, Tae Hee; Lee, Hae‐Hyeog; Lee, Seung Hun; Wang, Tong

doi:10.6118/jmm.2014.20.1.1

Cited by 57 publications

(49 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…35 Several mechanisms may be supposed to be responsible for this BP rise: increase of salt sensitivity, decrease of nitric oxide production, overexpression of type 1 angiotensin II receptor. 36 Estrogens are supposed to protect from high BP levels by strengthening the correlation between pressure and salt excretion and promoting nitric-oxide synthetize activity and nitric oxide production. In particular, a previous study that involves more that >22,000 Italian female patients showed that menopause has a double risk of developing sustained hypertension.…”

Section: Age: Gender-related Differencesmentioning

confidence: 99%

“…43 However, in literature some differences were described for diuretics with better response among women. During menopause, women presented a greater salt-sensitivity, so diuretics may be useful to promote renal sodium excretion and BP reduction, 36 moreover a beneficial effect on calcium metabolism, with a consequent inferior risk of hip fracture, was described. 44 Diuretics present also different side effects according to gender: among women sodium and potassium reduction, while an increased risk of gout among men.…”

Section: Pharmacological Treatment: Gender-related Differencesmentioning

confidence: 99%

See 1 more Smart Citation

Young FADOI and gender medicine: sex gender differences in cardiovascular disease

Ciarambino

Gino

Gnerre³

et al. 2018

Ital J Med

View full text Add to dashboard Cite

IntroductionBernardine Healy, in an editorial of 1991 on the NEJ The Yentl Syndrome, 1,2 showed how cardiovascular disease in women is understudied, under diagnosed and undertreated. The adverse ischemic heart disease is leading cause of death, less common in young women, where myocardial infarction (MI) mortality is two-fold higher in women younger than 50 years compared with age-matched men. The literature suggests that when women look like men, with male-pattern obstructive cardiovascular diseases (CHD), they are more likely to be diagnosed and treated like men. Two new analyses suggest that the Yentl syndrome is alive and well 10 years later. The first event in women takes about 10-20 years later than men. Women are more likely than men to have highrisk presentations and less likely to manifest central chest pain. 1,3 Pain in the upper back, arm, neck, and jaw, as well as unusual fatigue, dyspnea, indigestion, nausea/vomiting, palpitations, weakness, and a sense of dread, occur more frequently in women compared with men. The absence of chest pain or silent heart attack is more common in women than in men (35% vs 28%). So, women often turn later to the doctor and are treated less aggressively.1 Cardiovascular disease is the most common cause of death and hospitalization in worldwide. Recognition of important gender differences plays an important role in cardiovascular disease prevention. New sensitivity about gender differences, and particularly attention among women, will be necessary for more analytic view about cardiovascular disease in both sexes. Possible causesThe Framingham study already described the risk factors for CHD in women; then the INTERHEART, conducted in 52 countries around the world, identified nine risk factors, measurable and modifiable. These factors measurable and modifiable are: i) smoking; ii) hypertension; iii) diabetes; iv) dyslipidemia; v) abdominal obesity (waist/hip ratio); vi) stress and psychosocial factors; vii) physical inactivity; viii) low intake of fruits and vegetables; ix) alcohol. More risk factors greatly multiply the probability of infarction. 4,5 These risk factors explain more than 90% of myocardial infarctions and in about 96% of CHD in women. For example, in women, it has been shown that family and marital stress increase the risk of Young FADOI and gender medicine: sex gender differences in cardiovascular disease ABSTRACTWe have evaluated gender-related differences in cardiovascular disease. In particular, in coronary heart disease, atrial fibrillation, arterial hypertension, venous thromboembolism and diabetes mellitus. ©Copyright T. Ciarambino et al., 2018 Licensee PAGEPress, Italy Italian Journal of Medicine 2018 12:23-31 doi:10.4081/itjm.2018.864 Italian Journal of Medicine 2018; volume 12:23-31 N o n -c o m m e r c i a l u s e o n l y ischemic heart disease. In women there is another condition that simulates the coronary heart disease. This condition is the Takotsubo syndrome. [6][7][8][9][10][11][12][13][14][15][16] Depression is one aspect of psycho...

show abstract

Section: Age: Gender-related Differencesmentioning

confidence: 99%

Section: Pharmacological Treatment: Gender-related Differencesmentioning

confidence: 99%

Young FADOI and gender medicine: sex gender differences in cardiovascular disease

Ciarambino

Gino

Gnerre³

et al. 2018

Ital J Med

View full text Add to dashboard Cite

show abstract

“…Berdasarkan hasil dari penelitian (Kim, Kim, Lee, Lee, & Wang, 2014) dengan judul Postmenopausal hypertension and sodium sensitivity, menjelaskan bahwa mekanisme pengaturan ginjal untuk perbedaan gender dalam tekanan darah dan mengeksplorasi efek dari asupan garam pada tekanan darah (sensitivitas garam) pada wanita pra dan pasca-menopause. Diperoleh hasil bahwa prevalensi garam-sensitivitas meningkat dengan usia dan diet rendah garam telah terbukti membantu mengurangi tekanan darah sistolik (SBP) dan diastolik BP.…”

Section: Asupan Lemakunclassified

Korelasi Asupan Makanan, Stres, Dan Aktivitas Fisik Dengan Hipertensi Pada Usia Menopause

Yulistina

Deliana

Rustiana

2017

UJPH

View full text Add to dashboard Cite

AbstrakPeningkatan tekanan darah pada wanita usia menopause menunjukkan bahwa defisiensi estrogen mungkin menjadi kontributor untuk tekanan darah tinggi pada wanita lanjut usia sebesar 65 % sedangkan 35 % dapat dipengaruhi oleh faktor gaya hidup dan faktor lainnya. Penelitian ini bertujuan untuk menganalisis faktor gaya hidup terhadap hipertensi pada usia menopause di Puskesmas Tlogosari Wetan Semarang. Jenis penelitian ini kuantitatif dengan menggunakan desain cross sectional. Sampel pada penelitian sebanyak 50 orang. Pengukuran variabel-variabelnya menggunakan data primer dan sekunder. Analisis data menggunakan analisis univariat, bivariat uji Spearman rank, dan multivariat uji Regresi Logistik. Hasil penelitian menunjukkan ada hubungan yang bermakna antara aktivitas fisik, stres, asupan lemak, asupan natrium (p<0,05) terhadap hipertensi pada usia menopause. Hasil regresi logistik menunjukkan asupan natrium memiliki tingkat risiko lebih tinggi terhadap hipertensi (p=0,021). Kesimpulan: Asupan makanan, stres, dan aktivitas fisik merupakan faktor gaya hidup yang sangat berperan terhadap risiko hipertensi pada wanita menopause. Abstract

show abstract

“…This fact is attributed, in part, to estrogen deficiency. However, there seems to be the only one involved in the onset of post-menopausal hypertension [30].…”

Section: Neurology and Neuroscience Issn: 2386-687xmentioning

confidence: 99%