Postnatal structure of the sella turcica in Down syndrome

Russell, Bjørn G.; Kjær, Inger

doi:10.1002/(sici)1096-8628(19991119)87:2<183::aid-ajmg11>3.0.co;2-a

Cited by 56 publications

(66 citation statements)

References 20 publications

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“…Sella turcica dimensions reported by many researchers [11,15] are based on Caucasian populations and the data were mostly obtained from skull radiographs. Based on our investigation, it was observed that, this is the first time the sella turcica was investigated on computed tomography in the indigenous population.…”

Section: Discussionmentioning

confidence: 99%

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An Assessment of the Size of Sella Turcica Among Adult Nigerians Resident in Lagos

Olubunmi¹

2016

IJMI

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Abstract:One of the clinical significance of the sella turcica is the empty sella syndrome which is the condition of a shrunken or flattened pituitary gland; hence a familiarity with the sella turcica anatomy and radiological appearance is of great importance. The present study investigated the normal dimensions of the sella turcica and the relationship with gender and age in adult Nigerians resident in Lagos, using computed tomographs of patients who underwent CT head examination. This was carried out to determine if the dimensions of sella turcica vary with age, gender and race; this is with a view to providing normal, standard reference for the indigenous population in Nigeria. This study assessed: the length, the depth and the anteroposterior diameter of the sella turcica; 297 samples were obtained and analyzed using SPSS Windows Version 14.0. T-test was used for the statistical analysis and values obtained were expressed as mean±S.E.M. and P value ˂ 0.05 was considered statistically significant. The results showed the mean length of 9.81±0.094mm; the mean antero-posterior diameter of 11.37±0.090mm and the mean depth of 8.49±0.08mm. It was also observed that neither the age group nor the gender of the patients is a determinant of the sella turcica dimensions. Furthermore, the males tend to have slightly larger sella turcica dimensions than the females and the values from the present study are lower than those reported in Caucasian studies. The size of pituitary gland can be roughly estimated from the dimensions of sella turcica obtained from radiological methods in pathological conditions since disease conditions of the "master gland" ultimately affect the size of the sella turcica.

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Section: Discussionmentioning

confidence: 99%

“…The sella turcica is usually demarcated by a dense, thin white line in lateral radiographs. It is sometimes more important to recognize this feature than to estimate the size of the fossa [11].…”

Section: Introductionmentioning

confidence: 99%

An Assessment of the Size of Sella Turcica Among Adult Nigerians Resident in Lagos

Olubunmi¹

2016

IJMI

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“…Agenesis of all third molars was seen in 52% of our sample, similar to the 55% reported by Shapira et al 19 Because of the frequent agenesis of all third molars in our sample, we explored whether this occurrence was associated with any specific craniofacial features. Russel and Kjaer 41 hypothesized that an association in DS between the sella turcica structure and the innervations determined occurrence of tooth agenesis due to the proximity of sella to the trigeminal ganglion. In our cephalometric analysis, specific measurements (pituitary fossa diameter, sella turcica elevation from FHP, posterior maxillary vertical height, and the vertical distance of sella from the pterygomaxillary fissure) were included to explore whether the sella and vertical growth of the infrasellar region were differentially affected in individuals with DS having maxillary hypodontia and agenesis of all third molars, respectively.…”

Section: Discussionmentioning

confidence: 99%

Prevalence and patterns of permanent tooth agenesis in Down syndrome and their association with craniofacial morphology

Suri¹,

Tompson²,

Atenafu³

2011

The Angle Orthodontist

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Objective: To (1) document the prevalence and patterns of hypodontia (permanent tooth agenesis) in Down syndrome (DS) and (2) explore whether maxillary or mandibular hypodontia or simultaneous agenesis of all third molars was associated with differential alterations of the craniofacial morphology. Materials and Methods: Longitudinal panoramic radiographs of 25 white patients with DS (12 male, 13 female; mean age, 15.1 years) treated at The Hospital for Sick Children, Toronto, Ontario, Canada, were evaluated to document hypodontia. Cephalometric measurements of subjects with maxillary or mandibular hypodontia or agenesis of all third molars were compared with those of subjects without hypodontia in these regions using analysis of covariance adjusted for age, gender, and proportion of other missing teeth in the total number of missing teeth. Results: Hypodontia was seen in 92% of the sample when third molars were considered and in 56% when third molars were not considered. Hypodontia was more prevalent and severe in females. The most frequently agenetic teeth were maxillary and mandibular third molars . maxillary lateral incisors . mandibular second premolars . mandibular incisors . maxillary second premolars . maxillary second molars. Simultaneous agenesis of all third molars was seen in 52% of the sample. Maxillary hypodontia was not associated with significant regional craniofacial differences, while mandibular hypodontia was associated with decreased mandibular length and increased ramus:body ratio. Agenesis of all third molars was not associated with significant craniofacial differences. Conclusions: Hypodontia is widely prevalent in DS. The effect of the syndrome appears to be stronger than that of regional hypodontia in differentially altering the craniofacial morphology. (Angle Orthod. 2011;81:260-269.)

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“…These changes can also occur in some syndromes and craniofacial abnormalities that affect the craniofacial region such as primary hypopituitarism, Williams syndrome, growth hormone deficiency, Cushing's syndrome, lumbosacral myelomeningocele, the presence of intrasellar adenomas, empty sella syndrome, and Rathke's cleft cysts and aneurysms [5,8,15,31,43]. By means of MRI, Baleriaux et al [9] concluded that macroadenomas, meningiomas, craniopharyngiomas, and cysts are more probable causes of deformation of the neighboring bony structures.…”

Section: Introductionmentioning

confidence: 99%

Morphometric analysis of the sella turcica in Turkish individuals with different dentofacial skeletal patterns

Mağat

Şener

2018

Folia Morphol

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Postnatal structure of the sella turcica in Down syndrome

Cited by 56 publications

References 20 publications

An Assessment of the Size of Sella Turcica Among Adult Nigerians Resident in Lagos

An Assessment of the Size of Sella Turcica Among Adult Nigerians Resident in Lagos

Prevalence and patterns of permanent tooth agenesis in Down syndrome and their association with craniofacial morphology

Morphometric analysis of the sella turcica in Turkish individuals with different dentofacial skeletal patterns

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