Postoperation of cervical cancer with intestine metastasis: a case report and literature review

Abstract

BackgroundCervical cancer can infiltrate locally and directly spread to adjacent organs including the vagina, peritoneum, urinary bladder, ureters, rectum, and paracervical tissue, but the intestine metastasis from cervical cancer is extremely rare, which can easily be misdiagnosed.Case presentationHere, we report a case about a 45-year-old postoperative cervical cancer patient with metastases to small intestine and sigmoid colon who presented abdominal distention and dull pain due to intestinal obstruction. The patient underwent exploratory laparotomy, and two intestinal segments including the tumors were resected. The postoperative pathological diagnosis illustrated sigmoid colon and terminal ileum metastatic squamous cell carcinoma.ConclusionsThis case demonstrates that intestine metastasis must be considered in the differential diagnosis of acute abdomen in patients with cervical cancer even at an early tumor stage.

Uterine cervical squamous cell carcinoma with duodenal metastasis causes obstructive jaundice

“…Metastasis to small intestine is not common and the incidence is only 4 ‐10.6% in patients with primary cancer, especially in stomach, colon and ovary cancer. Intensive immune protection system in small intestine is considered as the main reason [8].…”

“…Compared to its large proportion of gastrointestinal tract, the incidence of small bowel malignancy is extremely lower than other gastrointestinal malignancies [10]. Several hypotheses have been discussed for this unique presentation [8]. First, liquefied chyme in small intestine cause less irritation and trauma to mucosa.…”

“…Finally, the entire mucosal layer turns over in 4 – 7 days. This high turnaround rate decreases tumor growing [5,6,8].…”

Metastatic Cutaneous Squamous Cell Carcinoma with Gastrointestinal Involvement: A Case Report

“…Primary colonic SCC has been described in case reports [12, 13] and several small series [14] and has been estimated to constitute up to 0.2% of primary colon cancers [15]. However metastatic colonic involvement, though reported to rarely occur with lung [5, 6], esophageal [4], and cervical primary cancers [7], has not been reported from a cutaneous SCC. A single case of a synchronous metastatic SCC to the colon was reported by Ito et al in 2016 [16].…”

“…Metastatic SCC without a known primary site constitutes about 5% of all cancers of unknown primary site [3]. Gastrointestinal involvement as a manifestation of metastatic SCC is relatively uncommon, yet has been reported in the literature, including several cases identifying colonic involvement from known primary locations including the esophagus [4], lung [5, 6], and cervix [7]. However, this is the first report that identifies a gastrointestinal metastasis manifesting as recurrent disease from a cutaneous primary source without evidence of active disease elsewhere on multiple imaging studies.…”