Postoperative Analgesia After Peripheral Nerve Block for Podiatric Surgery

Reinhart, Douglas J.; Stagg, Kelly S.; Walker, Kevin G.; Wang, Wei Peng; Parker, Colleen M.; Jackson, Heidi H.; Walker, Edward B.

doi:10.1097/00115550-200009000-00012

Cited by 2 publications

(1 citation statement)

References 9 publications

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“…У дослідженні, де вивчався кеторолак як ад'ювант для лідокаїну, він покращив аналгезію при операціях на стопі [31]. У порівняльному дослідженні кеторолаку й дексмедетомідину він (кеторолак) не показав переваг у тривалості чи швидкості настання блоку [32].…”

Section: оглядunclassified

Adjuvants in pain medicine. Selection of the drug depending on the desired effect – so which drug to choose?

Dmytrіiev

Lisak

Zaletska

2020

PMJUA

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To date, much research has focused on finding the ideal adjuvant for local anesthetics. Each of them can have different effects. In anesthesiology and pain medicine, depending on the purpose, one or another effect may be desirable. For example, in some situations it is desirable to accelerate the onset of action or prolong the duration of the block, in others the desired effect may be a “response to intravascular administration”, it should also be borne in mind that not all adjuvants are allowed for intrathecal administration.

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Section: оглядunclassified

Adjuvants in pain medicine. Selection of the drug depending on the desired effect – so which drug to choose?

Dmytrіiev

Lisak

Zaletska

2020

PMJUA

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Analgesic Efficacy of Preoperative Parecoxib Sodium in an Orthopedic Pain Model

Desjardins¹,

Traylor

Hubbard

2004

Journal of the American Podiatric Medical Association

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The efficacy and safety of preoperative intravenous administration of parecoxib sodium, a novel parenteral prodrug of a cyclooxygenase-2 selective inhibitor, in treating postoperative pain resulting from bunionectomy were evaluated in 50 patients who were part of a larger cohort of orthopedic and podiatric patients. Following bunionectomy, the median time to rescue medication (survival analysis) was 4 hours 18 min (95% confidence interval, 3 hours 4 min to 4 hours 37 min) in the placebo group, 7 hours 5 min (95% confidence interval, 3 hours 20 min to >24 hours) in the 20-mg parecoxib sodium group, and 10 hours 43 min (95% confidence interval, 4 hours 42 min to 14 hours 7 min) in the 40-mg parecoxib sodium group (significant for 40-mg parecoxib sodium versus placebo). Four or more hours after surgery, the mean pain-intensity (categorical) score was significantly lower in both parecoxib sodium groups than in the placebo group. Preoperative administration of parecoxib sodium was well tolerated and significantly reduced postoperative pain in patients who had undergone bunionectomy.

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Postoperative Analgesia After Peripheral Nerve Block for Podiatric Surgery

Cited by 2 publications

References 9 publications

Adjuvants in pain medicine. Selection of the drug depending on the desired effect – so which drug to choose?

Adjuvants in pain medicine. Selection of the drug depending on the desired effect – so which drug to choose?

Analgesic Efficacy of Preoperative Parecoxib Sodium in an Orthopedic Pain Model

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