Postoperative analgesia with tramadol and indomethacin for diagnostic curettage and early termination of pregnancy

Khazin, Vadim; Weitzman, S; Rozenzvit-Podles, E.; Ezri, Tiberiu; Debby, A.; Golan, Abraham; Evron, Shmuel

doi:10.1016/j.ijoa.2011.03.002

Cited by 8 publications

(6 citation statements)

References 17 publications

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“…NSAIDs have been used for pain relief in several gynecology procedures, such as episiotomies, pregnancy terminations, and dilation and curettage, as well as in gynecological clinical conditions, such as dysmenorrhea [19,20,21]. Although data are available regarding the use of NSAIDs in routine gynecology procedures, the effect of rectal NSAIDs for pain relief in Pipelle endometrial biopsies has not been evaluated.…”

Section: Introductionmentioning

confidence: 99%

Vaginal Misoprostol versus a Rectal Nonsteroidal Anti-Inflammatory Drug to Reduce Pain during Pipelle Endometrial Biopsies: A Prospective, Randomized, Placebo-Controlled Trial

Telli

Aydın²,

Öge

et al. 2014

Gynecol Obstet Invest

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Background: To evaluate and compare the efficacy of vaginal misoprostol and a rectal nonsteroidal anti-inflammatory drug (NSAID) on pain relief during Pipelle endometrial biopsies in a placebo-controlled randomized study. Methods: One hundred and fifty-one women who had an indication for a Pipelle endometrial biopsy were randomized into three groups as follows: group 1, vaginal misoprostol; group 2, rectal NSAID, and group 3, control. After the procedure, the women were asked to record their pain severity on a visual analog scale. The secondary outcome of the study was patient acceptability, and vasovagal symptoms and analgesic requirements after the procedure were also recorded. Results: There were no statistically significant differences in the demographic characteristics of the patients. The primary study outcome was the comparison of the median visual analog scale pain scores of groups 1 and 2 versus group 3 (controls); no statistically significant differences were found (p = 0.502). In addition, the patient acceptability (Likert scale), vasovagal symptoms and analgesic requirements after the procedure were similar among the groups (p = 0.204, 1 and 0.546, respectively). Conclusion: Our study did not demonstrate a reduction in pain relief during Pipelle endometrial biopsies for patients receiving vaginal misoprostol or a rectal NSAID when compared to patients receiving placebo treatment.

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Section: Introductionmentioning

confidence: 99%

Vaginal Misoprostol versus a Rectal Nonsteroidal Anti-Inflammatory Drug to Reduce Pain during Pipelle Endometrial Biopsies: A Prospective, Randomized, Placebo-Controlled Trial

Telli

Aydın²,

Öge

et al. 2014

Gynecol Obstet Invest

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“…Preoperative administration of rectal suppositories of tramadol 100 mg provided superior postoperative analgesia compared to rectal suppositories of indomethacin 100 mg after diagnostic curettage and early termination of pregnancy. [ 27 ] In contrast, preoperative oral administration of pregabalin 100 mg, which is commonly used for multimodal analgesia, did not reduce postoperative pain after hysteroscopy. [ 26 ] Preoperative administration of IV parecoxib 40 mg reduced only dynamic pain, but not resting pain, after minor gynecological surgery.…”

Section: Discussionmentioning

confidence: 99%

The effect of preoperative intravenous lidocaine on postoperative pain following hysteroscopy

Lee

et al. 2020

Medicine

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Background: The use of hysteroscopy for the diagnosis and treatment of uterine and endometrial abnormalities is often associated with postoperative pain. This randomized controlled trial aimed to assess the efficacy of preoperative intravenous (IV) lidocaine in reducing pain after hysteroscopy. Methods: In total, 138 patients undergoing elective hysteroscopy at the CHA Bundang Medical Center, Seongnam, Korea were randomly assigned to a control group (n = 69) or a lidocaine group (n = 69), which received normal saline or IV lidocaine at 1.5 mg/kg, respectively. The primary outcome was the incidence of postoperative pain. Results: The incidence of pain was significantly lower in the IV lidocaine group than in the control group at the post-anesthesia care unit (27.3% vs 68.2%, P < .001). The visual analog scale (0–10) score (median [interquartile range]) was lower in the IV lidocaine group than in the control group (0 [0–2]) vs 2 [0–4]), P < .001). The use of rescue analgesics and postoperative nausea and vomiting were similar between the 2 groups. This study demonstrated that administering 1.5 mg/kg of preoperative IV lidocaine can be a simple method to reduce incidence of pain after hysteroscopy. Conclusion: Preoperative bolus administration of 1.5 mg/kg of IV lidocaine may be used to decrease incidence of pain after hysteroscopy under general anesthesia.

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“…Although opioid analgesics are the most widely used drugs for controlling postoperative pain, some authors have emphasized the use of intravenous paracetamol to improve postoperative pain and increase patient satisfaction following this type of surgery [29][30][31][32] . Th e effi cacy of paracetamol alone in the treatment of mild-to-moderate postoperative pain and its place in combination treatment were investigated [33][34][35] . Studies of combination treatment have shown that paracetamol has an opioid reducing eff ect and that it signifi cantly reduces patient need for total opioids, thus increasing patient overall satisfaction with analgesic therapy 33,36 .…”

Section: Discussionmentioning

confidence: 99%

Analgesic Effect – Comparison of Paracetamol Administered Intermittently and Through Patient-Controlled Analgesia Pump after Lumbar Discectomy: a Prospective Clinical Study

Kurtović

Rotim

Batinica³

et al. 2017

acc

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SUMMARY -Lumbar discectomy is the most common surgical treatment for intervertebral disc extrusion. Postoperative pain is a common clinical problem that greatly aff ects the length of hospitalization, functional status and patient quality of life. Th e aim of this study was to compare the postoperative analgesic effi cacy of paracetamol administered intermittently and through patient-controlled analgesia (PCA) pump following single level lumbar discectomy. Patients who underwent elective lumbar discectomy of intervertebral disc extrusion at the L4-L5 level diagnosed by magnetic resonance of the lumbosacral spine were included in the study. Pain was assessed at regular intervals for 48 hours through a shortened version of McGill pain questionnaire translated in the Croatian language. When pain was monitored as a summarized variable for each measurement, PCA group signifi cantly stood up after 24 hours with better perception of pain compared to the intermittent group (c 2 -test, p<0.05). Adequate pain relief is an important aspect of postoperative care in spinal surgery patients. Postoperative use of paracetamol through PCA pump achieved better pain control and pain management versus postoperative use of intermittent paracetamol analgesia after lumbar discectomy.

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Postoperative analgesia with tramadol and indomethacin for diagnostic curettage and early termination of pregnancy

Cited by 8 publications

References 17 publications

Vaginal Misoprostol versus a Rectal Nonsteroidal Anti-Inflammatory Drug to Reduce Pain during Pipelle Endometrial Biopsies: A Prospective, Randomized, Placebo-Controlled Trial

Vaginal Misoprostol versus a Rectal Nonsteroidal Anti-Inflammatory Drug to Reduce Pain during Pipelle Endometrial Biopsies: A Prospective, Randomized, Placebo-Controlled Trial

The effect of preoperative intravenous lidocaine on postoperative pain following hysteroscopy

Analgesic Effect – Comparison of Paracetamol Administered Intermittently and Through Patient-Controlled Analgesia Pump after Lumbar Discectomy: a Prospective Clinical Study

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