Keloid is a benign fibrous growth, which presents in scar tissue of predisposed individuals. It is a result of irregular wound healing, but the exact mechanism is unknown. However, it is possible that several factors such as age of onset, sex, cause of scarring, blood groups, anatomical site, presence of family history and number of injured sites (multiple/single) have an important role in keloid formation and consequentially in predicting keloid's behavior in response to treatment and prognosis. In this mini review, we have demonstrated these risk factors of keloids in detail.