Postoperative Epidural Fibrosis

Abstract

A statistical comparison of the clinical picture in the 2 surgically treated groups failed to reach statistical significance. Nevertheless, a trend toward better clinical picture in the steroid mix group was observed. Paradoxically, when statistically compared, the rate of EF build-up was found greater in the steroid-treated group. A 5% statistical significance was established in the correlation between the presence of EF and the patients' subjective rating (difference between input and output visual analog scale).

Two-photon imaging of chronically implanted neural electrodes: Sealing methods and new insights

“…Proliferation of dura mater/fibrous tissue following surgical intervention has been well documented with post-surgical epidural fibrosis, as well as in craniotomies with either no sealant or PEG or alginate based sealants (Masopust et al, 2009; Nunamaker and Kipke, 2010; Preul et al, 2003). It has also been reported that fibrous encapsulation of epidurally implanted silicone electrocorticography grids with no sealant can occur as quickly as one week, with fibrous tissue ultimately between 300-700 μm thick (Schendel et al, 2014).…”

Hérnia discal lombar

“…A fibrose peridural pode fixar as raízes e a dura-máter aos tecidos circundantes, comprometendo a nutrição e a atividade dinâmica do segmento; a alteração de fluxos arteriais e venosos de estruturas sensíveis à deformação mecânica, como o gânglio da raiz dorsal, tem impacto clínico considerável, manifestando-se com dor, paresia e parestesias (43) . O ligamento amarelo forma uma barreira anatômica para as raízes, dura-máter e gordura epidural, protegendo essas estruturas da compressão causada pelos tecidos circundantes; por isso, a sua preservação pode resultar em melhor prognóstico em relação à formação de fibrose epidural pós-discectomia (44) .…”

Results of Lumbar Endoscopic Adhesiolysis Using a Radiofrequency Catheter in Patients with Postoperative Fibrosis and Persistent or Recurrent Symptoms After Discectomy

“…1,2,4 Epidural fibrosis is mentioned in the literature as a common cause of pain after lumbar spine surgery and has been implicated in 8% to over 60% of cases of "failed back surgery syndrome" (FBSS), [3][4][5][6][7] despite several studies refuting any association. [8][9][10][11][12] Moreover, recent literature suggests that magnetic resonance imaging (MRI) may not be the most sensitive method for the diagnosis of epidural fibrosis. Using epiduroscopy as a diagnostic method, Bosscher and Heavner report severe fibrosis in 83% of their patients with persistent or recurrent symptoms after lumbar surgery.…”