Postoperative hypoparathyroidism in patients after total thyroidectomy - experience of a tertiary center in Romania

Martin, Carmen Sorina; Andrei, Marian; Parfeni, Ovidiu; Sîrbu, Anca; Barbu, Carmen; Giulea, Cosmin; Miron, Adrian; Andrei, Florin; Fica, Simona

doi:10.1530/endoabs.65.p419

Cited by 1 publication

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“…In this review, analysis was limited to studies with more than 500 participants. (5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15) These studies are shown in detail in Table 1. Transient hypoPT varied in definition regarding length, presence or absence of symptoms, and/or availability of PTH measurements.…”

Section: Postsurgical Hypoptmentioning

confidence: 99%

“…Many patients develop transient hypoPT after anterior neck surgery, but most of these cases resolve within 6 months to 1 year of surgery. (5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15) This narrative review will focus exclusively on the epidemiology and health care burden of chronic hypoPT (present for more than 6 months after surgery or from birth) and its complications.…”

Section: Introductionmentioning

confidence: 99%

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Epidemiology and Financial Burden of Adult Chronic Hypoparathyroidism

Björnsdóttir

Ing

Mitchell

et al. 2020

Journal of Bone and Mineral Research

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Chronic hypoparathyroidism is characterized by low serum calcium, increased serum phosphorus, and inappropriately low or decreased serum parathyroid hormone. This rare disorder is associated with a variety of complications. The prevalence, incidence, mortality, financial burden, and epidemiology of complications of this disorder are not well understood. This narrative review summarizes current information on the epidemiology and complications of chronic hypoparathyroidism. The reported prevalence of chronic hypoparathyroidism ranges from 6.4–37/100,000, and the incidence is reported to be 0.8–2.3/100,000/year. Mortality is not increased in studies from Denmark or South Korea but was increased in studies from Scotland and Sweden. The financial burden of this disorder is substantial because of increased health care resource utilization in two studies but not well quantitated. Recognized complications include hypercalciuria, nephrocalcinosis, kidney stones, and chronic kidney disease; low bone turnover and possibly upper extremity fractures; cardiac and vascular calcifications; basal ganglia calcifications, cataracts, infections, neuropsychiatric complications, and difficulties with pregnancy. This review concludes that chronic hypoparathyroidism is a rare disorder associated with significant morbidity that may not increase overall mortality but is associated with a substantial financial burden. © 2022 The Authors. Journal of Bone and Mineral Research published by Wiley Periodicals LLC on behalf of American Society for Bone and Mineral Research (ASBMR).

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