Postoperative Mortality Among Patients With Inflammatory Bowel Diseases: A Systematic Review and Meta-analysis of Population-Based Studies

Post‐operative complications in elderly onset inflammatory bowel disease: a population‐based study

“…8 We observed only 2 thromboembolic events in early post-operative setting. A recent meta-analysis showed that infectious post-operative complications in UC ranged from 10%-45% with a main incidence of 20% in population-based studies with elderly patients at higher risk especially in UC setting.…”

“…7 An increased risk of post-operative complication and mortality has been reported from referral tertiary centres in elderly onset IBD population. 8,9 However, data on post-operative complication in this population are limited, and the prevalence of these complications and the underlying associated factors remain unknown.…”

“…diagnosed after the age of 60, 139 patients required a first intestinal resection and were followed-up 6 years[2][3][4][5][6][7][8][9][10]. A quarter of these patients underwent definitive stoma.…”

Elective colectomy for severe ulcerative colitis may reduce mortality more than medical therapy

“…It is important to consider the increased mortality of emergent surgery, as well as the medical optimisation with newer biologics to avoid surgery. A meta-analysis of studies from 1990 to 2015 found that postoperative mortality for emergent colectomy was significantly greater than elective colectomy without significant decrease in mortality over time (5.3% vs 0.7%; p<0.05) 2. While these findings are noteworthy, most patients who are 50 years of age or older have significant comorbidities, which may complicate the decision regarding surgical management.…”

Editorial: Smoking Cessation for Crohn’s Disease: Clearing the Haze

“…Most patients with Crohn's disease require ongoing medical management with immunomodulators and biologics that impose toxicity-associated immunosuppression ( 3 ). When these therapies fail to control disease activity or complications, patients with Crohn's disease face intestinal resection that is associated with postoperative morbidity and mortality ( 4 ). Within 10 years of diagnosis, nearly half of patients with Crohn's disease require a bowel resection ( 5 ), and up to 25% undergo a repeated operation within 5 years of the fi rst resection ( 6 ).…”