1999
DOI: 10.1093/bja/82.6.886
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Postoperative pain after adenoidectomy in children

Abstract: We have investigated if pain intensity or analgesic requirements in hospital predicted pain intensity, pain duration or analgesic requirements at home in 611 children, aged 1-7 yr, after day-case adenoidectomy. We also investigated if ketoprofen 0.3-3.0 mg kg-1, administered pre-emptively i.v. during operation, modified pain at home. In hospital, a prospective, randomized, double-blind, placebo-controlled study design was performed. A standard anaesthetic technique was used in all children and fentanyl i.v. wa… Show more

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Cited by 41 publications
(32 citation statements)
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“…Overdosing was more likely with ibuprofen both in dosage and frequency. No serious adverse events including gastric bleeding were reported in several clinical studies evaluating the efficacy of ketoprofen for longer durations in pain treatment in children [23][24][25]. In the present study only one patient had an allergy favoring urticaria in the ketoprofen group.…”
Section: Discussioncontrasting
confidence: 50%
“…Overdosing was more likely with ibuprofen both in dosage and frequency. No serious adverse events including gastric bleeding were reported in several clinical studies evaluating the efficacy of ketoprofen for longer durations in pain treatment in children [23][24][25]. In the present study only one patient had an allergy favoring urticaria in the ketoprofen group.…”
Section: Discussioncontrasting
confidence: 50%
“…[3][4][5][6][7] Inadequate analgesia is prevalent after outpatient pediatric surgery 3,[6][7][8][9][10] and is the most common reason for unplanned hospital admissions. 11 In children, suboptimal analgesia can result in sleep disturbance, behavioural changes and vomiting.…”
mentioning
confidence: 99%
“…2 Indeed, researchers outside the United States suggested high levels of pain after tonsillectomy and adenoidectomy, as well as undertreatment of postoperative pain by parents. [3][4][5][6][7][8][9][10][11] The majority of those studies, however, had methodologic limitations such as small sample sizes, limited use of validated pain measures, and lack of a standardized approach to anesthesia and surgery.…”
mentioning
confidence: 99%