Postoperative Pain Control

Garimella, Veerabhadram; Cellini, Christina

doi:10.1055/s-0033-1351138

Cited by 381 publications

(289 citation statements)

References 42 publications

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“…2. Changes in PPI after preemptive analgesia with nimesulide, metamizole sodium and placebo as a function of time of NSAIDs [14].…”

Section: Resultsmentioning

confidence: 99%

Analysis of Postoperative Pain After Extraction of Impacted Mandibular Third Molars and Administration of Preemptive Analgesia

Neychev¹,

Chenchev²,

Simitchiev³

2017

JofIMAB

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Objective: Postoperative pain control after extraction of impacted mandibular third molars is important for patients because of the effect of pain symptoms on the healing process and quality of life. The objective of this study is to make a quantitative and qualitative assessment of the postoperative pain in patients to whom preemptive analgesia was administered.Material and Methods: This is a randomised, placebo-controlled study in 80 patients who underwent surgical removal of impacted mandibular third molars. The patients were divided into three groups -with the preemptive administration of placebo, metamizole sodium and nimesulide. The short form of the McGill Pain Questionnaire (SF-MPQ) and the Visual Analogue Scale (VAS) were used for assessment and analysis of postoperative pain.Results: For the first 24 hours after molar extraction the comparison of the values of the various pain components showed a superior effect of the preemptive analgesia with nimesulide for the alleviation of sensory and total pain compared to metamizole sodium and placebo. In all three groups, pain intensity was highest at postoperative hour 6.Conclusion: Preemptive use of NSAIDs in the extraction of impacted mandibular third molars reduces the perception of postoperative pain and its intensity.

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“…2. Changes in PPI after preemptive analgesia with nimesulide, metamizole sodium and placebo as a function of time of NSAIDs [14].…”

Section: Resultsmentioning

confidence: 99%

Analysis of Postoperative Pain After Extraction of Impacted Mandibular Third Molars and Administration of Preemptive Analgesia

Neychev¹,

Chenchev²,

Simitchiev³

2017

JofIMAB

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“…The different modalities (patient controlled/"as needed"), routes (oral, IV, regional and neuraxial) and agents (opioid/non-opioid) used can determine a modifiable regimen. Their approach includes preoperative Acetaminophen and Ketorolac, intraoperative wound infiltration, and postoperative Acetaminophen, Ibuprofen, PCIA and Oxycodone [23].…”

Section: Discussionmentioning

confidence: 99%

Pain Management in Weight Loss Surgery: Aiming for Multimodal Approach

Gamboa¹

2016

AOWMC

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Weight loss surgery (WLS) is an effective group of procedures with a low rate of complications, preventing or treating several cardiovascular co morbidities associated with morbid obesity. Pain management in the preoperative needs special consideration in this population because of different aspects, specially the theoretical need for opioid avoidance, generally used in the postoperative of major surgeries. This literature review assesses the available information on analgesic strategies for WLS, with a special approach on multimodal settings and possible alternatives. Well-controlled studies are needed to determine the level of recommendation for individual therapies and multimodal regimens.

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“…This is often best accomplished with a multimodal approach. 1 Analgesia administered before the painful stimulus occurs may prevent or substantially reduce subsequent pain or analgesic requirements. Pre-emptive analgesia can be administered via local wound infiltration, peripheral nerve blocks, epidural or systemic administration prior to surgical incision.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of efficacy of bupivacaine and bupivacaine plus clonidine in transversus abdominis plane (TAP) block for postoperative analgesia: a prospective, randomized, double blind, comparative study

Mir

Gani

et al. 2017

Int J Res Med Sci

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Background: Pain is the commonest symptom encountered postoperatively and hence multimodal analgesia is tried to overcome it. In this study, we have compared bupivacaine and bupivacaine plus clonidine in transversus abdominis plane (TAP) block for postoperative analgesia in patients undergoing lower abdominal surgeries under spinal anaesthesia. Methods: Sixty ASA I and II patients in the age range of 18-60 years undergoing various lower abdominal surgeries were randomly divided into two groups, who were operated after giving spinal block using 2.5 ml of 0.5% hyperbaric bupivacine and 25ug of fentanyl. At the end of surgical procedure tranversus abdominis plane (TAP) block was given by giving 25 ml of injection bupivacaine 0.25% in group I and 25 ml of 0.25% of bupivacaine with 1 ug.kg-1 of clonidine in group II. Quality of analgesia was assessed by visual analogue scale (VAS), categorical pain scoring system and frequency of rescue analgesia given and duration was assessed with the time at which first rescue analgesia was given. Side effects of clonidine such as sedation, bradycardia and hypotension were also noted. The hemodynamic parameters like heart rate (HR), systolic blood pressure (SBP) and diastolic blood pressure (DBP) were noted for both the groups. Results: Demographic characteristics like age, weight, sex, ASA class and type of surgeries were comparable in both groups. SBP, DBP and HR were less in group II than in group I and was statistically significant (p-value<0.05). The overall mean VAS score in group I was 3.03 ± 1.57 and group II was 1.72 ± 1.02 with p-value of 0.0005 and hence better quality of analgesia in group II. Categorical pain scoring system also showed statistically better scores in group II than group I. The duration of analgesia which was calculated by mean time for first rescue analgesia in group I was 6.38 ± 2.56 hours and group II was 14.23 ± 4.63 hours with a p-value of <0.0001 and the difference was statistically significant. The mean number of doses of rescue analgesia in group I for the first 24 hours was 1.37 ± 0.89 and in group II was 0.60 ± 0.62 with a p-value of 0.0003 and the difference was statistically significant. Group II patients showed more sedation scores than group I patients (p-value <0.05). None of the patients had any episode of bradycardia or hypotension. Conclusions: Addition of clonidine 1 ug.kg-1 to 25 ml of 0.25% bupivacaine compared to 25 ml of 0.25% bupivacaine alone in tranverse abdominis plane (TAP) block improves quality of analgesia, increases duration of postoperative analgesia and decreases postoperative analgesic requirements with minimal side effects.

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Postoperative Pain Control

Cited by 381 publications

References 42 publications

Analysis of Postoperative Pain After Extraction of Impacted Mandibular Third Molars and Administration of Preemptive Analgesia

Analysis of Postoperative Pain After Extraction of Impacted Mandibular Third Molars and Administration of Preemptive Analgesia

Pain Management in Weight Loss Surgery: Aiming for Multimodal Approach

Evaluation of efficacy of bupivacaine and bupivacaine plus clonidine in transversus abdominis plane (TAP) block for postoperative analgesia: a prospective, randomized, double blind, comparative study

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