Postoperative pyoderma gangrenosum

Faghihi, Gita; Abtahi‐Naeini, Bahareh; Nikyar, Zahra; Jamshidi, Kioumars; Bahrami, Abdulrahman

doi:10.4103/0022-3859.147042

Cited by 9 publications

(10 citation statements)

References 8 publications

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“…PSPG results in aggravation of the operative wound which becomes hollow, painful and purulent, simulating from all points of view an infectious cause. However, it should be mentioned that antibiotics are ineffective and surgical debridement worsens the condition due to a pathergic response [7][8][9]. In our case, the diagnosis of PSPG was made based on the unusual flare-up of the operative wound, the existence of old cribriform scars on the legs suggestive of a previous PG and the clinical appearance of the ulceration around the surgical incision.…”

Section: Discussionmentioning

confidence: 79%

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Post-Partum Pyoderma Gangenosum Following a Cesarean Section

Diallo¹,

Diop²,

Ba³

et al. 2017

Dermatol Case Rep

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The occurrence of Pyoderma gangrenosum (PG) during pregnancy or postpartum has rarely been reported. These forms can also occur on a recent scar facilitated by the pathergy phenomenon. A 25-year-old woman showed an abruptly worsening of a post-caesarean wound that evolved rapidly into a painful, purulent, extensive ulcer with breakdown of sutures, along with fever and leukocytosis despite antibiotic therapy. The diagnosis of postoperative PG was evoked on the unusual course of the surgical wound, the existence of old cribriform scars on the legs, the clinical appearance of the ulceration around the surgical incision and confirmed by histology, as well as the favourable outcome under systemic corticosteroid. This case raises once again the issue of the possible relationship between pregnancy and PG. In our case, pregnancy could have triggered the PG, and the Caesarean section facilitated its clinical expression by the pathergy phenomenon. Thus, pregnancy could be in the same way as chronic inflammatory diseases, such as arthritis, inflammatory bowel disease and haematological disorders, a triggering or exacerbating factor of PG.

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Section: Discussionmentioning

confidence: 79%

“…This phenomenon explains the preferential location of the PG for the lower limbs. This pathergy phenomenon can sometimes be linked with a surgical incision [7].…”

Section: Discussionmentioning

confidence: 99%

Post-Partum Pyoderma Gangenosum Following a Cesarean Section

Diallo¹,

Diop²,

Ba³

et al. 2017

Dermatol Case Rep

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“…Pyoderma gangrenosum characterized by painful progressive necrosis of the wound margins and the border of lesions typically is undermined and violaceous [16]. …”

Section: Discussionmentioning

confidence: 99%

Successful Treatment of Facial Acne Fulminans: Antimicrobial Agents and Oral Prednisolone as Promising Regimes

Siadat

Bostakian

Abtahi‐Naeini

et al. 2017

Case Reports in Dermatological Medicine

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“…Ulcerative PG is the most common type and is the primary manifestation of post-operative PG [ 1 , 5 ]. Pathergy, a phenomenon in which skin subjected to minor or major trauma will rapidly develop PG, is the underlying principle in post-operative PG [ 5 ]. Clinically, patients develop fevers and severe pain around the incision sites [ 2 , 3 , 5 ].…”

Section: Introductionmentioning

confidence: 99%

Post-Operative Pyoderma Gangrenosum: A Long Journey for a Patient with Myelodysplastic Syndrome

Tagliaferri¹

2020

Cureus

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Pyoderma gangrenosum (PG) is an inflammatory neutrophilic dermatosis, characterized by painful and erythematous papules, pustules or vesicles that rapidly become ulcerative and necrotic. These ulcers have multiple sub-types and can develop anywhere on the body. There are different postulations as to the mechanisms of development for each sub-type. More than half of patients with PG have an underlying disease, with the highest prevalence being inflammatory bowel disease (IBD), followed by inflammatory arthritis and hematological disorders. Post-operative PG should be considered in any patient undergoing surgery who subsequently develops characteristic necrotic lesions with delayed wound healing, fever and severe localized pain. The clinical manifestations and treatment may differ slightly depending on the type and cause of PG. Herein, we present a patient with myelodysplastic syndrome and arthritis, who underwent surgery for diverticulosis complicated by colovaginal fistula formation, and subsequently developed a very prolonged course of post-operative pyoderma gangrenosum. This report will address the types of PG, their various manifestations and pathogenesis, as well as the management specific to patients with myelodysplastic syndrome. It is our intent to better understand the sub-types in order to predict and prevent post-operative PG.

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Postoperative pyoderma gangrenosum

Cited by 9 publications

References 8 publications

Post-Partum Pyoderma Gangenosum Following a Cesarean Section

Post-Partum Pyoderma Gangenosum Following a Cesarean Section

Successful Treatment of Facial Acne Fulminans: Antimicrobial Agents and Oral Prednisolone as Promising Regimes

Post-Operative Pyoderma Gangrenosum: A Long Journey for a Patient with Myelodysplastic Syndrome

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