Postoperative radiotherapy after radical prostatectomy for prostate carcinoma: the experience of the Brescia Radium Institute

Abstract

Postoperative radiotherapy improves RFS and reduces the risk of local recurrence. The best results are obtained with early postoperative treatment ("adjuvant"); adjuvant radiotherapy of high-risk forms yields better results if performed with PSA less than or equal to 1 ng/ml.

Salvage versus adjuvant radiotherapy after radical prostatectomy: argument for adjuvant radiotherapy

“…The 5-year biochemical disease-free (bNED) rates range from 61.3% to 90.9% for the ART groups and 31% to 66.4% for the delayed therapy groups. Three series have reported superior 10-year bNED rates for the ART group compared with the SRT group: Teh and colleagues 7 with 90.9% versus 54.5% (p = 0.001), Caraffini and colleagues 8 with 38% versus 28% (p < 0.01) and Pacholke and colleagues 9 with 66% versus 22% (p < 0.001).…”