“…66,71 The topical medical therapy remains the first-line treatment for post-keratoplasty glaucoma, independently of the technique of corneal transplantation and equally to general glaucoma medical treatment. 66,68,72,73 Most cases with post-keratoplasty glaucoma respond positively to medical treatment; 25,66,68,74 however, adverse side effects of some eye drops and effects on graft failure, long-term survival, and optical clarity should be discussed. The commonly used beta-adrenergic blockers, such as Timolol, may cause a decrease in corneal epithelial barrier function and dry-eyelike surface changes.…”