Postrenal Azotemia in a Gastric Cancer Patient Revealed the Coincidence of Ureteral Metastasis and Contralateral Ureteral Stone: A Case Report

Guitynavard, Fateme; Zadeh, Seyed Saeed Tamehri; Rakebi, Mohammad Mehdi; Javadi, Arezoo Eftekhar; Aghamir, Seyed Mohammad Kazem

doi:10.1159/000520507

Cited by 3 publications

(2 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Regardless of the primary site of the tumor, ureteral metastasis is often a sign of advanced disease, which worsens the prognosis [5] . CECT examination has improved the diagnosis of spontaneous ureteral metastasis, whereas in the past the diagnosis was made post-mortem [6] .…”

Section: Discussionmentioning

confidence: 99%

Ureteral metastasis from gastric cancer after two years of subtotal gastrectomy: a case report

Pennisi

Giordano

Lentini

et al. 2022

Radiology Case Reports

View full text Add to dashboard Cite

True ureteral metastases from gastric cancer are extremely rare. Only a few cases of this condition have been reported. CT is the first-line imaging technique and may aid the diagnosis, even if the definitive diagnosis is histologic. We report a case of a 45-year-old female with a history of gastric cancer who underwent subtotal gastrectomy and presented 2 years later with ureteral metastasis and subsequently renal pelvis metastasis in absence of peritoneal involvement. A biopsy was required to rule out primary urothelial carcinoma and make a well-timed and proper diagnosis. We describe the pathologic and radiological features of this case, followed by a brief review of the literature included in the discussion.

show abstract

Section: Discussionmentioning

confidence: 99%

Ureteral metastasis from gastric cancer after two years of subtotal gastrectomy: a case report

Pennisi

Giordano

Lentini

et al. 2022

Radiology Case Reports

View full text Add to dashboard Cite

show abstract

“…In these cases, it is hypothesized that the tumor may develop in tissues with shared embryologic origins with the kidney or in metanephric structures that aberrantly persist beyond gestation ( 8 – 10 , 13 ). In the few reported cases of eccRCC without kidney involvement, most were treated with surgical resection without reports of recurrence during post-surgical surveillance ( 8 – 15 ). To our knowledge, there are only two reported cases in which systemic treatment was administered to the patient, with either tyrosine kinase inhibitors (TKIs) or chemotherapy.…”

Section: Introductionmentioning

confidence: 99%

Case Report: Exceptional response to nivolumab plus cabozantinib in a patient with extrarenal clear cell renal cell carcinoma

Jansen,

Choi,

Evans

et al. 2023

Front. Oncol.

View full text Add to dashboard Cite

Extrarenal clear cell renal cell carcinoma (eccRCC) is a rare type of RCC that arises in areas other than the kidney. Given its rarity, consensus guidelines for optimal treatment of eccRCC have not been established, and the literature is lacking any reports of patient response to systemic therapy and any reports of administration of immunotherapy to patients with ecRCC. Here, we present the case of a patient in their 60s with eccRCC arising in the spleen. The patient underwent splenic resection and then received systemic therapy, due to disease recurrence, with a combination of immunotherapy (IO) and tyrosine kinase inhibitor targeted therapy (VEGF-TKI). The patient had an excellent and durable response to this therapeutic regimen with minimal adverse effects, completing 2 years of therapy of nivolumab and cabozantinib. At the time of this report, the disease remains stable. This case demonstrates that combination therapy with IO+VEGF-TKI represents a reasonable and well-tolerated treatment option with activity in eccRCC and reveals interesting correlative data, including nests of stem-like CD8+T-cell infiltration in tumor tissue, which provide important biological context to this patient’s exceptional therapeutic response.

show abstract

Metachronous ureteral metastasis of a gastric adenocarcinoma: a case report and review of literature

Alla,

Chekrine,

Bouchbika

et al. 2023

J Med Case Reports

View full text Add to dashboard Cite

Background Ureteral metastasis from gastric cancers are rare and can be a cause of ureteral obstruction. There have been few published case reports in the literature. In this paper, we report an additional case and a review of the literature of all the previous reported cases. Case presentation A 67 years old North African women who was treated four years before for a gastric adenocarcinoma, presented with abdominal pain. Imaging and endoscopy showed a mural stenosis of the left ureter, without any other abnormality. Histopathology confirmed the gastric origin of the metastasis. A palliative chemotherapy was foreseen, but due to the deterioration of the general condition of the patient, she received palliative care. We have also reviewed the literature and reported the previously published cases of ureteral metastasis from gastric cancer. Conclusions It is worth recalling that in a context of neoplasia and with the presence of signs of ureteral obstruction, it is important to keep in mind the possibility of a ureteral metastasis.

show abstract

Postrenal Azotemia in a Gastric Cancer Patient Revealed the Coincidence of Ureteral Metastasis and Contralateral Ureteral Stone: A Case Report

Cited by 3 publications

References 5 publications

Ureteral metastasis from gastric cancer after two years of subtotal gastrectomy: a case report

Ureteral metastasis from gastric cancer after two years of subtotal gastrectomy: a case report

Case Report: Exceptional response to nivolumab plus cabozantinib in a patient with extrarenal clear cell renal cell carcinoma

Metachronous ureteral metastasis of a gastric adenocarcinoma: a case report and review of literature

Contact Info

Product

Resources

About