Postsurgical intraocular pressure elevation

Tuberville, Audrey W.; Tomoda, T; Nissenkorn, I; Wood, Thomas O.

doi:10.1016/s0146-2776(83)80062-7

Cited by 26 publications

(6 citation statements)

References 8 publications

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“…Larger donor buttons relative to recipient host beds have been associated with better postoperative IOP control [132,133], although another study did not support this finding [134]. Studies on combined cataract and PKP procedures have reported no increased risk of elevated IOP postoperatively [26,135,136]. Franca et al did not observe a difference in postoperative IOP elevations in those undergoing combined procedures versus PKP alone [45].…”

Section: Preoperative Considerationsmentioning

confidence: 99%

Graft failure: III. Glaucoma escalation after penetrating keratoplasty

Greenlee

Kwon

2008

Int Ophthalmol

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Glaucoma after penetrating keratoplasty is a frequently observed post-operative complication and is a risk factor for graft failure. Penetrating keratoplasty performed for aphakic and pseudophakic bullous keratopathy and inflammatory conditions are more likely to cause postoperative glaucoma compared with keratoconus and Fuchs' endothelial dystrophy. The intraocular pressure elevation may occur immediately after surgery or in the early to late postoperative period. Early postoperative causes of glaucoma include pre-existing glaucoma, retained viscoelastic, hyphema, inflammation, pupillary block, aqueous misdirection, or suprachoroidal hemorrhage. Late causes include pre-existing glaucoma, angle-closure glaucoma, ghost cell glaucoma, suprachoroidal hemorrhage, and steroid-induced glaucoma. Determining the cause of IOP elevation can help guide therapeutic intervention. Treatments for refractory glaucoma include topical anti-glaucoma medications such as beta-adrenergic blockers. Topical carbonic anhydrase inhibitors, miotic agents, adrenergic agonists, and prostaglandin analogs should be used with caution in the post-keratoplasty patient, because of the possibility of corneal decompensation, cystoid macular edema, or persistent inflammation. Various glaucoma surgical treatments have reported success in post-keratoplasty glaucoma. Trabeculectomy with mitomycin C can be successful in controlling IOP without the corneal toxicity noted with 5-fluorouracil. Glaucoma drainage devices have successfully controlled intraocular pressure in postkeratoplasty glaucoma; this is, however, associated with increased risk of graft failure. Placement of the tube through the pars plana may improve graft success compared with implantation within the anterior chamber. In addition, cyclophotocoagulation remains a useful procedure for eyes that have refractory glaucoma despite multiple surgical interventions.

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Section: Preoperative Considerationsmentioning

confidence: 99%

Graft failure: III. Glaucoma escalation after penetrating keratoplasty

Greenlee

Kwon

2008

Int Ophthalmol

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“…1 Since then numerous investigators have described this postoperative complication and proposed various mechanisms to describe its onset. [2][3][4][5][6][7][8][9] Initially, the use of α -chymotrypsin was linked to the increased frequency in postoperative IOP elevation. Later, Rich 2 showed that αchymotrypsin was not responsible for this increase.…”

Section: Introductionmentioning

confidence: 99%

“…An increase in IOP immediately after cataract extraction was first reported in 1962 by Gormaz 1 . Since then numerous investigators have described this postoperative complication and proposed various mechanisms to describe its onset 2–9 . Initially, the use of α‐chymotrypsin was linked to the increased frequency in postoperative IOP elevation.…”

Section: Introductionmentioning

confidence: 99%

Intraocular pressure development after cataract surgery: a prospective study in 50 dogs (1998–2000)

Chahory

Clerc

Guez

et al. 2003

Veterinary Ophthalmology

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“…Interaocular pressure (IOP) increase after intracapsular (Kirsch 1964;Rich et al 1974) and extracapsular cataract extraction (Tuberville et al 1983) has been decribed previously. An average peak is reached at a mean time of 6.8 h after intracapsular surgery (Rich et al 1974).…”

mentioning

confidence: 98%

The effect of betaxolol and timolol on postoperative intraocular pressure

Vuori

Ali‐Melkkilä

1993

Acta Ophthalmologica

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Postoperative intraocular pressure (IOP) elevation is a well documented phenomenon after cataract surgery. Many pharmacological agents have been used to prevent this complication. We conducted a randomized double-blind, placebo-controlled study to evaluate the effect of topical betaxolol and timolol on postoperative IOP after extracapsular cataract extraction and intraocular lens implantation. One hundred and twenty patients were randomly divided into three groups. At the end of the operation, the patients were given one drop of 0.5% betaxolol, 0.5% timolol or placebo solution into the lower cul-de-sac of the operated eye. IOP was measured preoperatively and five and twenty-four h postoperatively. There was a significant rise in IOP in the placebo and betaxolol groups but not in the timolol group five h postoperatively. IOP was significantly higher in all groups twenty-four h after the operation than preoperatively. Betaxolol did not have any significant effect on the postoperative IOP, but timolol was effective in preventing the early IOP rise. The differences in the antagonist effects of these drugs and the possible role of beta 2-receptors in mediating the aqueous humour flow are discussed.

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Postsurgical intraocular pressure elevation

Cited by 26 publications

References 8 publications

Graft failure: III. Glaucoma escalation after penetrating keratoplasty

Graft failure: III. Glaucoma escalation after penetrating keratoplasty

Intraocular pressure development after cataract surgery: a prospective study in 50 dogs (1998–2000)

The effect of betaxolol and timolol on postoperative intraocular pressure

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