Posttraumatic Pancreatitis Four Days after Renal Injury with Massive Retroperitoneal Hematoma

Kiriyama, Masamichi; Jitsuiki, Kei; Muramatsu, Ken‐ichi; Furusawa, Hoshiko; Moriya, Soshi; Yanagawa, Youichi

doi:10.1155/2021/6693259

Cited by 2 publications

(2 citation statements)

References 17 publications

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“…To our knowledge, this was the first reported case of fatal iAAA induced by urosepsis from a vesico-enteric fistula and/or acute pancreatitis complicated with multiple organ failure. Gallbladder stones, unstable circulation, and/or hypothermia in the present case may have played part in the development of acute pancreatitis [3,4]. Extremely rarely, acute pancreatitis co-exists with abdominal aortic aneurysm, which might result in rupture [5].…”

Section: Discussionmentioning

confidence: 67%

Fatal Mycotic Aortic Aneurysmal Rupture Induced by Urosepsis From a Vesico-Enteric Fistula and/or Acute Pancreatitis

Muramatsu¹,

Nagasawa²,

Ishikawa³

et al. 2022

Cureus

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A 70-year-old unconscious man with hospital phobia was transported to our hospital. On arrival, he displayed consciousness disturbance, unstable circulation, and a hypothermic state. Based on the clinical symptoms, the results of whole body computed tomography (CT), and biochemical studies, he was diagnosed with urosepsis (induced by vesico-enteric fistula), hyperglycemic crisis, infectious abdominal aortic aneurysm (iAAA), gallbladder stone-induced pancreatitis, and multiple organ failure. He was treated with supportive therapy. The abdominal magnetic resonance image (MRI) revealed an abdominal aortic aneurysm (AAA) with an inflammatory aortic wall, paraaortic inflammatory lymph node swelling, and periaortic fat inflammation. His consciousness temporarily recovered, but he did not agree to undergo surgery. On day 28, he suddenly collapsed. We present a fatal case of iAAA induced by urosepsis from vesicoenteric fistula and/or acute pancreatitis, complicated by multiple organ failure. In aging societies, physicians should explore not only the cause of disease but also the severity of the pathology and define fatal complications in elderly patients.

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Section: Discussionmentioning

confidence: 67%

Fatal Mycotic Aortic Aneurysmal Rupture Induced by Urosepsis From a Vesico-Enteric Fistula and/or Acute Pancreatitis

Muramatsu¹,

Nagasawa²,

Ishikawa³

et al. 2022

Cureus

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“…Acute pancreatitis (AP), an inflammatory disease of the pancreas, is the leading cause of hospital admissions for gastrointestinal diseases worldwide [1,2]. The worldwide incidence rate of AP is 33.74 per 100,000 person-years, with a gradual increase in incidence [3,4].…”

Section: Introductionmentioning

confidence: 99%

Construction and validation of machine learning models for sepsis prediction in patients with acute pancreatitis

Liu,

Yao,

Liu

et al. 2023

BMC Surg

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Background This study aimed to construct predictive models for the risk of sepsis in patients with Acute pancreatitis (AP) using machine learning methods and compared optimal one with the logistic regression (LR) model and scoring systems. Methods In this retrospective cohort study, data were collected from the Medical Information Mart for Intensive Care III (MIMIC III) database between 2001 and 2012 and the MIMIC IV database between 2008 and 2019. Patients were randomly divided into training and test sets (8:2). The least absolute shrinkage and selection operator (LASSO) regression plus 5-fold cross-validation were used to screen and confirm the predictive factors. Based on the selected predictive factors, 6 machine learning models were constructed, including support vector machine (SVM), K-nearest neighbour (KNN), multi-layer perceptron (MLP), LR, gradient boosting decision tree (GBDT) and adaptive enhancement algorithm (AdaBoost). The models and scoring systems were evaluated and compared using sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), accuracy, and the area under the curve (AUC). Results A total of 1, 672 patients were eligible for participation. In the training set, 261 AP patients (19.51%) were diagnosed with sepsis. The predictive factors for the risk of sepsis in AP patients included age, insurance, vasopressors, mechanical ventilation, Glasgow Coma Scale (GCS), heart rate, respiratory rate, temperature, SpO2, platelet, red blood cell distribution width (RDW), International Normalized Ratio (INR), and blood urea nitrogen (BUN). The AUC of the GBDT model for sepsis prediction in the AP patients in the testing set was 0.985. The GBDT model showed better performance in sepsis prediction than the LR, systemic inflammatory response syndrome (SIRS) score, bedside index for severity in acute pancreatitis (BISAP) score, sequential organ failure assessment (SOFA) score, quick-SOFA (qSOFA), and simplified acute physiology score II (SAPS II). Conclusion The present findings suggest that compared to the classical LR model and SOFA, qSOFA, SAPS II, SIRS, and BISAP scores, the machine learning model-GBDT model had a better performance in predicting sepsis in the AP patients, which is a useful tool for early identification of high-risk patients and timely clinical interventions.

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Posttraumatic Pancreatitis Four Days after Renal Injury with Massive Retroperitoneal Hematoma

Cited by 2 publications

References 17 publications

Fatal Mycotic Aortic Aneurysmal Rupture Induced by Urosepsis From a Vesico-Enteric Fistula and/or Acute Pancreatitis

Fatal Mycotic Aortic Aneurysmal Rupture Induced by Urosepsis From a Vesico-Enteric Fistula and/or Acute Pancreatitis

Construction and validation of machine learning models for sepsis prediction in patients with acute pancreatitis

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