2021
DOI: 10.1097/psy.0000000000000920
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Posttraumatic Stress Disorder and the Associated Risk of Autoimmune Skin Diseases: A Nationwide Population-Based Cohort Study

Abstract: Objective: Posttraumatic stress disorder (PTSD) is known as a risk factor for various immune-related disorders; however, the association between PTSD and related autoimmune skin diseases (ASDs) remains unclear. This study aimed to investigate the association of PTSD with the risk of related ASDs. Methods: Participants were recruited from the National Health Insurance Research Database in Taiwan. We included 9801 patients with PTSD and 39,204 matched controls to assess the risk of developing ASDs. Cox regressio… Show more

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Cited by 7 publications
(5 citation statements)
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“…In addition to anxiety, other psychological factors such as PTSD may affect hair loss. A nationwide population-based cohort study indicated that the patients with PTSD had an increased risk of developing autoimmune skin diseases (ASDs), including alopecia areata (AA) [ 69 ]. Our univariate analysis showed that PTSD is significantly associated with MPHL.…”
Section: Discussionmentioning
confidence: 99%
“…In addition to anxiety, other psychological factors such as PTSD may affect hair loss. A nationwide population-based cohort study indicated that the patients with PTSD had an increased risk of developing autoimmune skin diseases (ASDs), including alopecia areata (AA) [ 69 ]. Our univariate analysis showed that PTSD is significantly associated with MPHL.…”
Section: Discussionmentioning
confidence: 99%
“…Apart from stress, the risk of developing psoriasis was significantly increased in patients with major depressive disorder or posttraumatic stress disorder than in the control group [ 162 164 ]. Even the association between parental common mental disorders (anxiety and depression) and offspring's risk of psoriasis has been determined [ 165 ].…”
Section: Psychological Stress and Other Mental Disordersmentioning
confidence: 99%
“…Otros estudios señalaron que los pacientes con estrés postraumático tenían un mayor riesgo de desarrollar enfermedades autoinmunes de la piel como la psoriasis, alopecia, ampollas autoinmunes y vitiligo. (Dai et al, 2021). En efecto, Liu et al (2022) investigaron el trastorno de estrés postraumático en 337 pacientes con vitiligo y hallaron que un tercio de los pacientes con vitiligo tenían Estrés postraumático y se confirmó que la décima parte desarrolló Trastorno de estrés Postraumático.…”
Section: Estrés Psicológico Y Vitiligounclassified
“…Otros estudios señalan al estrés psicológico como un factor precipitante en el desarrollo del vitiligo, el cual puede estar correlacionado con el género (Hamidizadeh et al, 2020), resultado compatible con estudios que indican que las mujeres con vitiligo tienen peor calidad de vida al compararse con hombres que poseen el diagnóstico, igualmente las mujeres casadas en comparación con mujeres solteras (Al-Sadi et al, 2015).La enfermedad, también está asociada a ciertos rasgos de la personalidad como la cavilación y la rumiación que prevalecen en el individuo con vitiligo (Do Bú et al; La evidencia científica tributa que el estrés psicológico es más común en el vitiligo que en otras enfermedades psicodérmicas (Dai et al, 2021;Mangini et al, 2022). El estrés agudo y crónico puede causar un desbalance en los circuitos neuronales que intervienen en funciones cognitivas como la toma de decisiones, acelerar los niveles de ansiedad y los cambios de humor, generando un desbalance que afecta la fisiología del sistema neuroendocrino, autónomo, inmune y metabólico (Oken, Chamine, & Wakeland, 2015).…”
Section: Discusionunclassified