This investigation provides descriptive information on substantive scale scores from the Minnesota Multiphasic Personality Inventory-2-Restructured Form (MMPI-2-RF) across four common service locations within Veterans Affairs (VA): PTSD clinical team, individual substance use treatment, primary medical care, and residential polytrauma rehabilitation. Test protocols for these four service settings are drawn from a national sample of all MMPI-2-RF and converted MMPI-2 administrations between January 1, 2008 and May 31, 2015 using the VA Mental Health Assist system at any VA across the United States. Frequency of substantive scale elevation and descriptive findings are examined. Results of this investigation suggest that there are differences between VA service locations on the MMPI-2-RF substantive scales, the magnitude of difference depends on the substantive scale examined, and the pattern of elevation within service location follows common clinical concerns for the settings. Implications for the clinical use, and research with, the MMPI-2-RF within the VA and with the veteran population are discussed.