Postural Tachycardia Syndrome: Clinical Features and Follow-up Study

Sandroni, Paola; Opfer‐Gehrking, Tonette L.; McPhee, Benjamin R.; Low, Phillip A.

doi:10.4065/74.11.1106

Cited by 181 publications

(168 citation statements)

References 12 publications

Supporting

Mentioning

147

Contrasting

Unclassified

Order By: Relevance

“…POTS is a type of orthostatic intolerance characterized most frequently by the occurrence of orthostatic-type symptoms such as palpitations, light headedness, and near-syncope without a concomitant drop in blood pressure. Our patient manifested many of the typical clinical features of POTS patients, as described by Sandroni et al [5]. She was young and female, consistent with the reported presentation age of 28:9 AE 9:5 years and a female:male ratio of 4:1.…”

Section: Discussionsupporting

confidence: 90%

“…The diagnostic criteria are: heart rate increase ¼ 30 bpm within 5 min of standing or upright tilt, heart rate of 120 min within 5 min of standing or upright tilt, development of orthostatic symptoms without orthostatic hypotension, and absence of a known cause of autonomic neuropathy [6,7]. The present patient met these criteria; i.e., her rate increase was dramatic and even greater than the reported increase (from 79 AE 13 to 112 AE 28; mean AE SD bpm) observed by Sandroni et al [5] The same group also noted the likely benefit of beta-blockers which were introduced successfully in our patient.…”

Section: Discussionsupporting

confidence: 53%

“…In addition, duration of symptoms was less than 5 years, increasingly frequent, as is the case with most patients with POTS. Her two biggest complaints-palpitations and light headedness-were noted in 89 and 95%, respectively, of the study group [5].…”

Section: Discussionmentioning

confidence: 87%

See 2 more Smart Citations

Temporal lobe epilepsy and postural orthostatic tachycardia syndrome (POTS)

Seeck¹,

Blanke²,

Zaim³

2002

Epilepsy & Behavior

View full text Add to dashboard Cite

We describe a 20-year-old woman suffering from right temporal epilepsy, behavioral disorder, and a complaint of paroxysmal palpitations accompanied by anxiety. Detailed cardiac evaluation revealed that the palpitations were due to episodes of marked sinus tachycardia secondary to a concomitant postural orthostatic tachycardia syndrome (POTS) and not of psychogenic origin as initially thought. Treatment with a beta-blocker resulted in the disappearance of palpitations and the associated anxiety. This is the first report of the coexistence of partial epilepsy and POTS. The recognition of such a syndrome in epileptic patients is important in order to offer appropriate therapy. Ó

show abstract

Section: Discussionsupporting

confidence: 90%

Section: Discussionsupporting

confidence: 53%

See 1 more Smart Citation

Temporal lobe epilepsy and postural orthostatic tachycardia syndrome (POTS)

Seeck¹,

Blanke²,

Zaim³

2002

Epilepsy & Behavior

View full text Add to dashboard Cite

show abstract

“…16 The standard autonomic testing used in this study, specifically HUT, is commercially available and provides the criterion standard for which POTS is diagnosed. [1][2][3] As such, our analysis of POTS during pregnancy is readily applicable to clinical practice. Our hope is that the data provided in this study will help clinicians make decisions in the management of pregnant women with POTS or those thinking of becoming pregnant who have POTS.…”

Section: Resultsmentioning

confidence: 99%

“…2 Overall, the prognosis of POTS has been reported to be favorable in follow-up studies, with 80% of patients reporting improvement and 60% becoming functionally normal. 3 Onset of POTS occurs predominantly between the ages of 15 and 50 years, 4 with a female predominance. 1,2,[5][6][7] The female-to-male ratio has been reported to be as high as 5:1.…”

confidence: 99%

Effect of Pregnancy on Postural Tachycardia Syndrome

Kimpinski

Iodice

Sandroni

et al. 2010

Mayo Clinic Proceedings

Self Cite

View full text Add to dashboard Cite

P ostural tachycardia syndrome (POTS) is defined as the development of orthostatic symptoms associated with an increase in heart rate (HR) greater than 30 beats/min. More severe cases are associated with a standing HR increase greater than 120 beats/min. 1 Orthostatic symptoms most often include light-headedness, palpitations, presyncope, and exacerbations with heat or exercise. 2 Overall, the prognosis of POTS has been reported to be favorable in follow-up studies, with 80% of patients reporting improvement and 60% becoming functionally normal. 3 Onset of POTS occurs predominantly between the ages of 15 and 50 years, 4 with a female predominance. 1,2,[5][6][7] The female-to-male ratio has been reported to be as high as 5:1. 8 Given the female predominance and the occurrence of POTS during the childbearing years, the effects of this disorder on pregnancy is often raised in clinical practice.ObjECTIvES: To compare the clinical presentation, autonomic dysfunction, and pregnancy outcomes in parous and nulliparous women with postural tachycardia syndrome (POTS) and in women with POTS before and after pregnancy. PATIENTS AND METHODS:This study consists of women who had at least 1 pregnancy during which time they met criteria for POTS between May 1993 and July 2009. All patients underwent standard autonomic testing. POTS was defined as a heart rate (HR) increase of greater than 30 beats/min on head-up tilt (HUT) with symptoms of orthostatic intolerance. Patients' charts were reviewed retrospectively to determine pregnancy outcomes. RESULTS:Clinical characteristics related to POTS did not differ between parous and nulliparous women except for disease duration (parous, 3.7±2.6; nulliparous, 2.1±2.2; P<.001). Autonomic dysfunction did not differ between groups (change in HR on HUT: parous, 42.6±12.0 beats/min; nulliparous, 41.3±10.6 beats/min; P=.39). Of 116 total pregnancies, adverse pregnancy outcomes were reported in 9% and maternal complications in 1%. No complication was related to POTS. There was a trend toward modest improvement in autonomic dysfunction before and after pregnancy (change in HR on HUT: before pregnancy, 38.1±22.7 beats/min; after pregnancy, 21.9±14.9 beats/min; P=.07). CONCLUSION:The long-term impact of pregnancy on POTS does not appear to be clinically important. However, there does appear to be a trend toward improvement in the short-term postpartum period. Adverse pregnancy events were similar to those seen in the general public and do not present a barrier to women with POTS who want to have children.Mayo Clin Proc. 2010;85(7):639-644 CASS = composite autonomic severity score; HR = heart rate; HUT = head-up tilt; OI = orthostatic intolerance; POTS = postural tachycardia syndrome; TST = thermoregulatory sweat test However, until recently published data have been minimal. A recent study in 22 women indicated that, although the effect on symptoms related to POTS during pregnancy varied, the actual pregnancy was not affected. 9 The objectives of this study were as follows: (1) to determine whether ...

show abstract

Postural Tachycardia Syndrome and Chronic Fatigue Syndrome

Grubb¹

2007

The Fainting Phenomenon

View full text Add to dashboard Cite

Postural Tachycardia Syndrome: Clinical Features and Follow-up Study

Cited by 181 publications

References 12 publications

Temporal lobe epilepsy and postural orthostatic tachycardia syndrome (POTS)

Temporal lobe epilepsy and postural orthostatic tachycardia syndrome (POTS)

Effect of Pregnancy on Postural Tachycardia Syndrome

Postural Tachycardia Syndrome and Chronic Fatigue Syndrome

Contact Info

Product

Resources

About