2024
DOI: 10.1002/tox.24251
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Potato protein hydrolysate inhibits RANKL‐induced osteoclast development by inhibiting osteoclastogenic genes via the NF‐κB/MAPKs signaling pathways

Yi‐Ju Chen,
Yen‐Hua He,
Yun‐Hsin Lo
et al.

Abstract: In recent times, there has been growing attention towards exploring the nutritional and functional aspects of potato protein, along with its diverse applications. In the present study, we examined the anti‐osteoclast properties of potato protein hydrolysate (PP902) in vitro. Murine macrophages (RAW264.7) were differentiated into osteoclasts by receptor activator of nuclear factor‐κB ligand (RANKL), and PP902 was examined for its inhibitory effect. Initially, treatment with PP902 was found to significantly prev… Show more

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