POTENSI EKSTRAK DAUN NANGKA (Artocarpus heterophyllus Lam.) SEBAGAI ANTIOKSIDAN ALAMI

Adnyani, Ni Made Rica Dwi; Parwata, I Made Oka Adi; Negara, I Made Sutha

doi:10.24843/jchem.2017.v11.i02.p10

Cited by 4 publications

(7 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Dark green jackfruit (A. heterophyllus) leaves that were picked randomly in the order of 3-5 from the shoots (Abadi et al, 2021) were collected, washed and then dried. Dried jackfruit leaves are then blended to form a powder (Adnyani et al, 2017). 200 grams of Jackfruit leaves powder was macerated with 1000 mL of ethanol as a solvent (ratio 1:5).…”

Section: Work Procedures Preparation Of Jackfruit Leaves Crude Extractmentioning

confidence: 99%

Effect of Giving Jackfruit (Artocarpus heterophyllus) Leaves Crude Extract as An Alternative Antibacterial of Edwardsiella tarda Bacteria In Vitro

Nilakandhi

Prajitno

Fadjar

et al. 2023

JAFH

View full text Add to dashboard Cite

Barriers to cultivation activities are disease attacks, one of which is caused by infection with the bacterium Edwardsiella tarda. Treatment efforts can be made using natural ingredients such as jackfruit (A. heterophyllus) leaves. This study aims to determine the content of antibacterial compounds in the jackfruit (A. heterophyllus) leaves crude extract and their effect on Edwardsiella tarda bacteria in vitro. The inhibition test used disc test with five different concentrations of jackfruit (A. heterophyllus) leaves crude extract with three replications: 75 mg/L, 150 mg/L, 225 mg/L, 300 mg/L and 375 mg/L with a comparison using two types of controls (positive with 5 mg/L chloramphenicol antibiotics and negative with no treatment) using Tryptone Soy Agar (TSA) media and incubated for 2x24 hours. The results of phytochemical screening proved that the jackfruit (A. heterophyllus) leaves crude extract contains flavonoids, alkaloids, tannins and saponins. Treatment E with a dose of 375 mg/L gave the highest inhibition of 7.80 mm and treatment A with a dose of 75 mg/L gave the lowest inhibition of 4.38 mm. The relationship between the treatment given to the test parameter in the form of the resulting inhibitory power obtained the equation y = 0.0111x + 3.6297 with an R2 value of 0.974 which means 97% of the treatment given in the form of crude extract of jackfruit (A. heterophyllus) leaves affects inhibition of bacteria E. tarda.

show abstract

Section: Work Procedures Preparation Of Jackfruit Leaves Crude Extractmentioning

confidence: 99%

Effect of Giving Jackfruit (Artocarpus heterophyllus) Leaves Crude Extract as An Alternative Antibacterial of Edwardsiella tarda Bacteria In Vitro

Nilakandhi

Prajitno

Fadjar

et al. 2023

JAFH

View full text Add to dashboard Cite

show abstract

“…Secara kemotaksonomi keledang berpotensi memiliki aktivitas sebagai tabir surya. (Adnyani et al, 2017).…”

Section: Pendahuluanunclassified

Uji Aktivitas Tabir Surya Ekstrak Metanol, Fraksi N-Heksana, Etil Asetat Dan Metanol-Air Daun Keledang (Artocarpus lanceifolius Roxb) Secara In Vitro

Marliana,

Isyahro,

Widodo

2023

JIS

View full text Add to dashboard Cite

Uji aktivitas tabir surya dari daun keledang (Artocarpus lanceifolius Roxb.) secara in vitro telah dilakukan. Penelitian ini bertujuan untuk mengetahui sifat tabir surya ekstrak metanol, fraksi n-heksana, etil asetat dan metanol-air dari daun keledang. Metode yang digunakan secara in vitro menggunakan spektrofotometer UV-Vis. Berdasarkan hasil uji fitokimia diketahui bahwa ekstrak metanol mengandung flavonoid, fenolik dan steroid/ triterpenoid. Fraksi n-heksana mengandung steroid/triterpenoid dan kuinon. Fraksi etil asetat mengandung flavonoid, fenolik, steroid/triterpenoid dan kuinon. Fraksi metanol-air mengandung flavonoid dan fenolik. Ekstrak metanol, fraksi n-heksana, etil asetat dan metanol-air juga menunjukkan adanya aktivitas tabir surya, berdasarkan nilai SPF (Sun Protection Factor) pada konsentrasi 25; 50; 100; 150; 200 dan 250 mg/L. Ekstrak metanol memiliki nilai SPF secara berturut adalah 4,44; 7,36; 15,15; 22,47; 31,25 dan 37,31 (minimal-ultra). Fraksi n-heksana memiliki nilai SPF secara berturut adalah 1,37; 2,23; 5,07; 7,51; 10,01 dan 12,74 (minimal-maksimal). Fraksi etil asetat memiliki nilai SPF secara berturut adalah 3,32; 7,20; 13,03; 19,54; 25,97 dan 30,60 (minimal-ultra). Fraksi metanol-air memiliki nilai SPF berturut adalah 5,23; 10,87; 21,48; 30,89; 36,01 dan 38,52 (sedang-ultra). Nilai SPF meningkat seiring dengan dengan peningkatan konsentrasi karena semakin tinggi konsentrasi maka semakin banyak senyawa aktif tabir surya yang terkandung dalam ekstrak dan fraksi tersebut. Pada daun keledang, fraksi metanol-air memiliki aktivitas tabir surya tertinggi diikuti ekstrak metanol, fraksi etil asetat dan fraksi n-heksana. Daun keledang berpotensi sebagai bahan tabir surya. Kata kunci: Artocarpus lanceifolius; in vitro; tabir surya

show abstract

“…Kandungan flavonoid yang terdapat pada tanaman diketahui mempunyai potensi sebagai antioksidan. Beberapa penelitian mengenai khasiat tanaman daun nangka sebagai antioksidan telah dilakukan diantaranya penelitian yang dilakukan [1] yang hasilnya menunjukkan bahwa ekstrak daun nangka memiliki aktivitas antioksidan sangat kuat.…”

Section: Pendahuluanunclassified

Evaluasi Granul Ekstrak Daun Nangka (Artocarpus heterophyllus L.) dengan Menggunakan Metode Granulasi Basah

et al. 2021

View full text Add to dashboard Cite

Jackfruit leaf (Artocarpus heterophyllus L.) is a potential plant that has passed pharmacological studies showing its anti-inflammatory, antibacterial, antiviral, anticancer, antihypertensive, and diuretic activities. The purpose of this study was to determine whether the granules of jackfruit leaf extract (Artocarpus heterophyllus L.) met the physical requirements of good granules. The first step in this research is to carry out the simplicia extraction process of jackfruit leaves using the maceration method using 96% ethanol as solvent. And in the manufacture of granules using the wet granulation method. In the study, the results of the evaluation of the granules of the angle of repose of formula I and formula IV were 24,220, formula II and formula III were 26,380. The average Granule Flow Rate Test for formula I is 3.4 seconds, formula II averages 2.91 seconds, formula III averages 2.59, and formula IV averages 2.75 seconds and falls into the cohesive range. The water content test in formulas I, II, III, and IV was 1%. And in the compressibility test of formula I the results are 11%, formula II is 7.85%, formula III is 8.99%, and formula IV is 3.92%. From these data, it can be concluded that the granules in formulas I, II, III, and IV have good physical properties because in the physical properties test all formulas meet the requirements.Keywords: Jackfruit leaves; granule evaluation; granules; wet granulation. AbstrakDaun Nangka (Artocarpus heterophyllus L.) adalah tanaman potensial yang telah melewati studi farmakologi yang menunjukkan adanya aktivitas antiinflamasi, antibakteri, antivirus, antikanker, antihipertensi, dan diuretik. Tujuan dari penelitian ini adalah mengetahui apakah granul ekstrak daun nangka (Artocarpus heterophyllus L.) memenuhi persyaratan fisik granul yang baik. Langkah pertama pada penelitian ini adalah dengan melakukan proses ekstraksi simplisia daun nangka menggunakan metode maserasi dengan menggunakan pelarut etanol 96%. Dan pada pembuatan granul dengan menggunakan metode granulasi basah. Pada penelitian didapatkan hasil evaluasi granul sudut diam formula I dan formula IV hasilnya 24,220, formula II dan formula III hasilnya 26,380. Uji Laju Alir Granul formula I rata-ratanya 3,4 detik, formula II rata-ratanya 2,91 detik, formula III rata-ratanya 2,59, dan formula IV rata-ratanya 2,75 detik dan masuk kedalam rentang kohesif. Uji Kadar air pada formula I, II, III, dan IV hasilnya adalah 1%. Dan pada uji kompresibilitas formula I hasilnya 11%, formula II 7,85%, formula III 8,99%, dan formula IV 3,92%. Dari data tersebut dapat disimpulkan bahwa granul pada formula I, II, III, dan IV memiliki sifat fisik yang baik karena pada uji sifat fisik granul semua formula memenuhi syarat. Kata kunci : Daun nangka; evaluasi granul; granul; granulasi basah.

show abstract

POTENSI EKSTRAK DAUN NANGKA (Artocarpus heterophyllus Lam.) SEBAGAI ANTIOKSIDAN ALAMI

Cited by 4 publications

References 0 publications

Effect of Giving Jackfruit (Artocarpus heterophyllus) Leaves Crude Extract as An Alternative Antibacterial of Edwardsiella tarda Bacteria In Vitro

Effect of Giving Jackfruit (Artocarpus heterophyllus) Leaves Crude Extract as An Alternative Antibacterial of Edwardsiella tarda Bacteria In Vitro

Uji Aktivitas Tabir Surya Ekstrak Metanol, Fraksi N-Heksana, Etil Asetat Dan Metanol-Air Daun Keledang (Artocarpus lanceifolius Roxb) Secara In Vitro

Evaluasi Granul Ekstrak Daun Nangka (Artocarpus heterophyllus L.) dengan Menggunakan Metode Granulasi Basah

Contact Info

Product

Resources

About