Potential Antimicrobial and Chemical Composition of Essential Oils from Piper caldense Tissues

Abstract

The essential oils from leaves, stems and roots of Piper caldense were analyzed by GC-MS. The antibacterial potential of the oils was evaluated against gram-negative bacteria and gram-positive bacteria. The major chemical constituents that were identified from various parts of this plant were α-cardinal, α-muurolol, tujopsan-2-β-ol and δ-cadiene in the leaves, valencene, pentadecane, elina-3,7-11-dieno α-terpineol in the roots and terpine-4-ol, α-terpineol, α-cadinol 2-β-ol in the stems. Tissue oils showed antibacterial activity against the bacteria tested except for Enterococcus faecalis. This is the first report of the biological activity and chemical composition essential oil of P. caldense.

Essential Oils from Neotropical Piper Species and Their Biological Activities

“…Piper caldense oils from different tissues displayed as major components α-cadinol (19.0%), α-muurolol (9.0%), and thujopsan-2β-ol (7.4%) (leaves); terpinen-4-ol (18.5%), α-terpineol (15.3%), and α-cadinol-2β-ol (9.8%) (stems); and pentadecane (35.7%), valencene (10.5%), and selina-3,7(11)-diene (5.4%) (roots). The samples were tested against E. coli , Klebsiella pneumoniae , Pseudomonas aeruginosa , S. aureus and B. subtilis using agar diffusion assay and showed moderate to weak bacterial activity with MIC value of 325 or 750 μg/mL in comparison to gentamicin (5.0 μg/mL) [ 54 ]. P. cernuum and P. regnellii EOs from leaves inhibited growth of S. aureus and Candida albicans when evaluated by agar diffusion assay.…”

“… Pueblo Bello, Cesar, Colombia Aerial parts (MWHD) α-Pinene (20.3%), β-pinene (32.3%), β-caryophyllene (6.3%) Antifungal, broth dilution assay ( Trichophyton rubrum , MIC 157 μg/mL; Trichophyton mentagrophytes , MIC 125 μg/mL); cytotoxic (Vero cells, IC 50 15.2 μg/mL) [ 121 ] P. caldense C. DC. Recife, Pernambuco state, Brazil Leaf (HD) δ-Cadinene (5.6%), thujopsan-2β-ol (7.4%), α-muurolol (9.0%), α-cadinol (19.0%) Antibacterial, agar diffusion assay ( Bacillus subtilis , Staphylococcus aureus , Klebsiella pneumoniae ) [ 54 ] P. caldense C. DC. Recife, Pernambuco state, Brazil Root (HD) Valencene (10.5%), pentadecane (35.7%), selina-3,7(11)-diene (5.4%) Antibacterial, agar diffusion assay ( Bacillus subtilis , Staphylococcus aureus , Escherichia coli , Klebsiella pneumoniae , Pseudomonas aeruginosa ) [ 54 ] P. caldense C. DC.…”

Secondary Metabolic Profile as a Tool for Distinction and Characterization of Cultivars of Black Pepper (Piper nigrum L.) Cultivated in Pará State, Brazil

“…In another study, the major compounds identified in the cultivar "Bragantina" were cubenol (14.55-21.53%), bicyclogermacrene (6.36-8.16%), and β-selinene (4.10-6.21%) [43]. The main component of "Bragantina" cultivar, α-muurolol, can also be found in other Piper species, such as P. amalago (5.0-9.3%) [44], P. caldense (9.0%) [45], P. cernuum Vell. (5.8%) [46], P. manausense (7.6%) [47], and P. sp.…”

Characterization and biological applications of gonadal extract of Paracentrotus lividus collected along the Mediterranean coast of Alexandria, Egypt

“…Also, hexadecenoic acid and octadecanoic acid were found to disrupt cytoplasmic membranes and induce DNA damage to Staphylococcus aureus and Pseudomonas aeruginosa [ 71 ]. Additionally, hexadecenoic acid, methyl ester inhibited the growth of Escherichia coli , Pseudomonas aeruginosa and Klebsiella bacterial strains [ 72 , 73 ], whereas Pentadecane, Octadecane, and Eicosane possess anti-bacterial activity against the tested bacteria [ 74 , 75 ]. Certain carotenoids induced lysozyme accumulation in the cell that digests bacterial cell walls [ 76 ] whereas, β-carotene and Astaxanthin inhibited Pseudomonas aeruginosa bacterial growth [ 77 , 78 ] and Neoxanthin caused growth inhibition in helicobacter pylori growth [ 79 ].…”