Potential antioxidant properties and hepatoprotective effects of an aqueous extract formula derived from three Chinese medicinal herbs against CCl4-induced liver injury in rats

Comparing the regenerative effects of silymarin and apricot on liver regeneration after partial hepatectomy in rats

“…Yang et al [7] dose of silymarin were two times higher and El-Adawi et al [9] dose was 7.5 times lower than ours, but Megahed et al [26] dose was one out of five from us. And the administration routes were same with Raskovic et al [25], Yang et al [7], ElAdawi et al [9], Megahed et al [26] and Chen et al [23] studies and different from Horvath et al study [7,9,[23][24][25][26]. And also SDOA rate (10%) was same with Vardi et al [6], Yilmaz et al [27] and Parlakpinar et al [28] studies, and two times more than Yilmaz et al [4,6,[27][28][29].…”

“…In mammalian body, the liver is the only organ that quickly regenerates after injury or surgical resection [2,7]. In the present study, silymarin dose was the same as Chen et al [23], two times higher than Horvath et al [24] and higher than Raskovic et al studies [25].…”

“…In the present study, silymarin dose was the same as Chen et al [23], two times higher than Horvath et al [24] and higher than Raskovic et al studies [25]. Yang et al [7] dose of silymarin were two times higher and El-Adawi et al [9] dose was 7.5 times lower than ours, but Megahed et al [26] dose was one out of five from us. And the administration routes were same with Raskovic et al [25], Yang et al [7], ElAdawi et al [9], Megahed et al [26] and Chen et al [23] studies and different from Horvath et al study [7,9,[23][24][25][26].…”

“…It is reported that, HCC is one of the most common cancers and fatal diseases and associated with high morbidity and mortality in the world. And because of HCC, surgical resection is to be the most optimal treatment approach, but only 10-20% of HCC patients are candidates for surgery, and also the reiterations can be as high as 50% within several years of surgery [7]. In preventive control attempts, the phytochemicals are properly accepted as beneficial pharmacological ingredients and they endorsed treatment options for various conditions.…”

“…In this context, it has been accepted that the natural dietary polyphenolics are obtained from variant fruits and vegetables. These are phytochemicals and bioactive food components, (as anthocyanidins, catechins, curcumin, genistein, lycopene, resveratrol, quercetin and β-caroten) [6][7][8]. Here, El-Adawi et al reported that dietary polyphenols have beneficial effect on human health by means of free radical scavenging, metal chelation and modulation of ISSN 0970-938X www.biomedres.info…”