2016
DOI: 10.4172/pharmaceutical-sciences.1000152
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Potential Antithrombotic Effects of Bupivacaine in Malignancies: An In Vitro Assesment Using Thromboelastography

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“…Akay et al 82 showed that the use of hetastarch in patients with gynecologic cancers resulted in hypocoagulable states compared to controls, characterized by ROTEM parameters such as increased CT and CFT and a reduced MCF; these results suggest that hetastarch may help reduce VTE in gynecologic surgeries. Additionally, Bilir et al 83 demonstrated via ROTEM analysis that bupivacaine results in hypocoagulopathic changes in women with gynecologic malignancies 81 …”
Section: Specific Malignancies and The Mac Identified By Vetsmentioning
confidence: 99%
“…Akay et al 82 showed that the use of hetastarch in patients with gynecologic cancers resulted in hypocoagulable states compared to controls, characterized by ROTEM parameters such as increased CT and CFT and a reduced MCF; these results suggest that hetastarch may help reduce VTE in gynecologic surgeries. Additionally, Bilir et al 83 demonstrated via ROTEM analysis that bupivacaine results in hypocoagulopathic changes in women with gynecologic malignancies 81 …”
Section: Specific Malignancies and The Mac Identified By Vetsmentioning
confidence: 99%