Potential Biosignificant Interest and Surface Activity of Efficient Heterocyclic Derivatives

Althagafi

Ahmed

2017

J Surfact & Detergents

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A series of novel fluorene derivatives were synthesized from the target compound N‐octadecyl‐9‐oxo‐9H‐fluorene‐4‐carboxamide (3), which led to new functionalized five‐ and six‐membered heterocyclic derivatives via reaction with various reagents. The synthesized compounds were allowed to react with propylene oxide to afford unique surface‐active properties. The chemical structures of the newly synthesized compounds were elucidated and confirmed by spectroscopic and analytical tools. The synthesized compounds have good surface activity and the biological degradation of these fluorene‐based surfactants was greater than 96% after 7 days.

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Fluorene Derivatives with Multi‐addressable Properties: Synthesis, Characterization, and Reactivity

Althagafi

Ahmed

2017

J Surfact & Detergents

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“…Overall, through our study of foam properties, Scheme 4. Synthesis of surface active agents (22)(23)(24)(25)(26). Table 1 Reaction conditions of propoxylated compounds.…”

Section: Surface and Interfacial Tensionmentioning

confidence: 99%

Synthesis, Surface, and Antimicrobial Activity of Hydrophobically Thiadiazole, Pyridazine, and Pyrimidine Systems Based on Surface Active Agents

Althagafi

Journal of Heterocyclic Chem

2018

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A series of hydrophobically thiadiazole, pyridazine, and pyrimidine were synthesized with surface and biological activities from cheap, available, and safe raw materials such as fatty acids. Thus, diazotizations of thiadiazole derivative 2 and malononitrile resulted a hydrazone derivative 3, which was used to construct various biologically active compounds with low toxicity, good solubility and biodegradation, surface properties with biological activity. The results revealed that these substances have the ability to reduce the surface tension, reduce the wetting time, varying degrees of foam and emulsifying stability, which makes use in the different industries. As well as their biodegradability, which confirms that these compounds are environmentally friendly to humans and the environment. Furthermore, the effect of these compounds against certain microorganisms has been studied and shown to be highly effective against the activity of these organisms.

“…These surface active agents are inexpensive to produce and have various applications in industry, because of applications as emulsifiers, foam stabilization, wetting agents, facilitate solubilization and several biotechnological processes [40][41][42][43][44][45][46]. Addition of number of moles of propylene oxide (10 moles) to the synthesized compounds (4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20) which have active hydrogen atoms in the presence of KOH as a catalyst produced nonionic surface active agents (21)(22)(23)(24)(25)(26)(27)(28)(29)(30)(31)(32)(33)(34)(35)(36)(37), respectively, which may have broader formulation flexibility. The structure of propoxylated products (21)(22)(23)(24)(25)…”

Section: Surface Activity Of the Synthesized Compoundsmentioning

confidence: 99%

“…Oleochemicals are necessary to a variety of applications such as plastics, surface treatments, paints, lubricants, pharmaceuticals, pesticides, detergents, soaps, textiles, and cosmetic [14][15][16][17][18][19][20]. Extending our past research in this area [21][22][23][24][25][26], we sought to prepare some new isoxazole, pyrazole, puran, pyridine and pyrimidine derivatives and evaluating their surface and biological activities to determine suitability for the applications above.…”

Section: Introductionmentioning

confidence: 99%

Synthesis of Potential Pharmaceutical Heterocycles as Surface Active Agents

Howsaway

2017

J Surfact & Detergents

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Isoxazole, pyrazole, pyran, pyridine and pyrimidine derivatives of fatty acids were synthesized as surface and bioactive heterocycles. Hydroxylation of these intermediates by propylene oxide produced easy-to-handle, efficient and quickly biodegradable surface active agents, which revealed the importance of their applications in safety for humans as well as the environment. These compounds showed good activity against bacteria and fungi, showing promise in applications of drugs, cosmetics, and pesticides.