Potential Effects of Methotrexate on Health: A Review
Patel Payal,
Nagda Girima
Abstract:Methotrexate (MTX) is a metabolite that functions as an antifolate, impeding DNA synthesis, repair, and cell replication. Its clinical uses include rheumatoid arthritis treatment and cancer treatments due to its anti-folate mechanism of action. This medication serves as the primary disease-modifying antirheumatic drug (DMARD) for individuals afflicted with dermatological, inflammatory, and autoimmune conditions. Methotrexate has a unique mode of action, both in terms of its usage as a chemotherapeutic drug and… Show more
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