Potential Effects of Sage powder, Sesame and Olive Oils on Lipid Profile and Liver Functions of Non-Alcoholic Fatty Liver Rats.

Abstract

The aim of this study was to investigate the effects of sage, sesame and olive oils alone and in combination with sage on total lipid (TL), total cholesterol (TC), triglyceride (TG), serum lipoprotein fractions (HDL-c, LDL-c and VLDL-c), liver enzymes and antioxidant enzymes, as well as histological changes of liver in obese nonalcoholic fatty liver disease (NAFLD) albino rats.A total of 72 adult male albino rats weighing (200 ± 10g) were used in this study. The rats were divided into two main groups: The first group (8 rats) fed on basal diet (BD) as control negative group (-ve). The second main group (64 rats) fed on high fat diet (HFD) for (8) weeks to induce non-alcoholic fatty liver disease (NLFLD). then rats were divided into (8 subgroups). One (8 rats) fed (HFD), as positive control