Potential Hurdles to ABO-Incompatible Living Donor Kidney Transplantation Without Augmented Immunosuppression

ABOi With Conventional Immunosuppression Alone–Antiblood Group Antibody Isn’t the Only Contributor to Antibody-Mediated Rejection and/or Thrombotic Microangiopathy

“…We thank Dr. Focosi et al and Dr. Krishan et al for their comments regarding the recent article describing ABOincompatible renal transplantation (ABOi) without antibody removal using conventional immunosuppression alone (1,2). In the manuscript, we highlighted the role of antiblood group antibody (ABGAb) titer as the major predictor of antibody-mediated rejection (AbMR) in ABOi.…”