Potential impact of B lineage mismatch on trivalent influenza vaccine effectiveness during the 2015–2016 influenza season among nursery school children in Suzhou, China

Wang, Yin; Chen, Liling; Cheng, Yun; Zhou, Suizan; Pang, Yuanyuan; Zhang, Jun; Greene, Carolyn M.; Song, Ying; Zhang, Tao

doi:10.1080/21645515.2017.1397868

Cited by 7 publications

(4 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The search terms identified 1408 studies from the six databases—282 from the Wanfang database, 472 from CNKI, 302 from VIP journal database, 282 from CBM, 130 from Web of Science, and 27 from PubMed. Our eligibility review identified 21 articles for including in the analyses [ 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 ] ( Figure 1 ). The 21 eligible studies were conducted between the 2010–2011 influenza season and the 2017–2018 influenza season.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Influenza Vaccine Effectiveness in Mainland China: A Systematic Review and Meta-Analysis

Yang

Zhao

et al. 2021

Vaccines

View full text Add to dashboard Cite

Influenza endangers human health but can be prevented in part by vaccination. Assessing influenza vaccine effectiveness (VE) provides scientific evidence for developing influenza vaccination policy. We conducted a systematic review and meta-analysis of studies that evaluated influenza VE in mainland China. We searched six relevant databases as of 30 August 2019 to identify studies and used Review Manager 5.3 software to analyze the included studies. The Newcastle–Ottawa scale was used to assess the risk of publication bias. We identified 1408 publications, and after removing duplicates and screening full texts, we included 21 studies in the analyses. Studies were conducted in Beijing, Guangzhou, Suzhou, and Zhejiang province from the 2010/11 influenza season through the 2017/18 influenza season. Overall influenza VE for laboratory confirmed influenza was 36% (95% CI: 25–46%). In the subgroup analysis, VE was 45% (95% CI: 18–64%) for children 6–35 months who received one dose of influenza vaccine, and 57% (95% CI: 50–64%) who received two doses. VE was 47% (95% CI: 39–54%) for children 6 months to 8 years, and 18% (95% CI: 0–33%) for adults ≥60 years. For inpatients, VE was 21% (95% CI: −11–44%). We conclude that influenza vaccines that were used in mainland China had a moderate effectiveness, with VE being higher among children than the elderly. Influenza VE should be continuously monitored in mainland China to provide evidence for policy making and improving uptake of the influenza vaccine.

show abstract

Section: Resultsmentioning

confidence: 99%

“…Ref. [ 38 ] * and [ 39 ] *: The original study method was cohort study, but used test-negative design method to analyze, so we showed the positive rate of tested-sample in Table 1 .…”

Section: Figurementioning

confidence: 99%

Influenza Vaccine Effectiveness in Mainland China: A Systematic Review and Meta-Analysis

Yang

Zhao

et al. 2021

Vaccines

View full text Add to dashboard Cite

show abstract

“…Classic influenza vaccines commonly induce antibodies to the viral surface antigens, hemagglutinin (HA) and neuraminidase (NA), mainly to their immunodominant hypervariable regions. Constant antigenic drift allows the virus easily to escape the action of these antibodies, reducing the effectiveness of vaccination and leading to a need for annual updating of vaccine strains in the seasonal influenza vaccines [95, 129]. The performance of seasonal influenza vaccines can be improved by increasing the speed of vaccine production and using new adjuvants and new vaccination strategies.…”

Section: Introductionmentioning

confidence: 99%

M2e-based universal influenza vaccines: a historical overview and new approaches to development

2019

View full text Add to dashboard Cite

The influenza A virus was isolated for the first time in 1931, and the first attempts to develop a vaccine against the virus began soon afterwards. In addition to causing seasonal epidemics, influenza viruses can cause pandemics at random intervals, which are very hard to predict. Vaccination is the most effective way of preventing the spread of influenza infection. However, seasonal vaccination is ineffective against pandemic influenza viruses because of antigenic differences, and it takes approximately six months from isolation of a new virus to develop an effective vaccine. One of the possible ways to fight the emergence of pandemics may be by using a new type of vaccine, with a long and broad spectrum of action. The extracellular domain of the M2 protein (M2e) of influenza A virus is a conservative region, and an attractive target for a universal influenza vaccine. This review gives a historical overview of the study of M2 protein, and summarizes the latest developments in the preparation of M2e-based universal influenza vaccines.

show abstract

“…Wang et al followed nursery school children and found that the effectiveness of the trivalent influenza vaccine was compromised in the 2015-6 season by B lineage mismatch. 17 Castrucci et al described how host factors can contribute to the heterogeneity of immune responses induced by influenza vaccines. 18 Moreover, Ward et al described attempts to standardize surrogate assays to predict vaccine efficacy, the dangers of over-reliance on reference serologic assays, the ways that manufacturers can exploit the existing regulatory framework to make their products 'look good' and the implications of this long-established system for the introduction of novel influenza vaccines.…”

mentioning

confidence: 99%

100 years since the 1918 influenza pandemic

Esposito

2018

Human Vaccines & Immunotherapeutics

View full text Add to dashboard Cite

Potential impact of B lineage mismatch on trivalent influenza vaccine effectiveness during the 2015–2016 influenza season among nursery school children in Suzhou, China

Cited by 7 publications

References 19 publications

Influenza Vaccine Effectiveness in Mainland China: A Systematic Review and Meta-Analysis

Influenza Vaccine Effectiveness in Mainland China: A Systematic Review and Meta-Analysis

M2e-based universal influenza vaccines: a historical overview and new approaches to development

100 years since the 1918 influenza pandemic

Contact Info

Product

Resources

About